Medical Subject Headings

Last uploaded: January 31, 2024

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Preferred Name	Cholinesterase Inhibitors
Synonyms	Cholinesterase Inhibitors, Reversible Irreversible Cholinesterase Inhibitors Anticholinesterase Agent Anticholinesterases Cholinesterase Inhibitors, Irreversible Inhibitors, Acetylcholinesterase Acetylcholinesterase Inhibitors Cholinesterase Inhibitor Anti Cholinesterase Anticholinesterase Acetylcholinesterase Inhibitor Anticholinesterase Drugs Anticholinesterase Drug Drugs, Anticholinesterase Agent, Anticholinesterase Agents, Anticholinesterase Drug, Anticholinesterase Inhibitors, Cholinesterase Anti-Cholinesterase Anticholinesterase Agents Inhibitors, Reversible Cholinesterase Anti Cholinesterases Inhibitors, Irreversible Cholinesterase Inhibitor, Acetylcholinesterase Anti-Cholinesterases Reversible Cholinesterase Inhibitors Inhibitor, Cholinesterase
Definitions	Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.
ID	http://purl.bioontology.org/ontology/MESH/D002800
altLabel	Cholinesterase Inhibitors, Reversible Irreversible Cholinesterase Inhibitors Anticholinesterase Agent Anticholinesterases Cholinesterase Inhibitors, Irreversible Inhibitors, Acetylcholinesterase Acetylcholinesterase Inhibitors Cholinesterase Inhibitor Anti Cholinesterase Anticholinesterase Acetylcholinesterase Inhibitor Anticholinesterase Drugs Anticholinesterase Drug Drugs, Anticholinesterase Agent, Anticholinesterase Agents, Anticholinesterase Drug, Anticholinesterase Inhibitors, Cholinesterase Anti-Cholinesterase Anticholinesterase Agents Inhibitors, Reversible Cholinesterase Anti Cholinesterases Inhibitors, Irreversible Cholinesterase Inhibitor, Acetylcholinesterase Anti-Cholinesterases Reversible Cholinesterase Inhibitors Inhibitor, Cholinesterase
AQL	AD AE AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
cui	C0008427 C0008426 C0001046 C0008425
DC	1
definition	Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.
DX	19650101
FX	D007306
HN	65; CHOLINESTERASE INHIBITORS, IRREVERSIBLE & CHOLINESTERASE INHIBITORS, REVERSIBLE were see under CHOLINESTERASE INHIBITORS 1975-83, were Prov 1971-74; CHOLINESTERASE INHIBITORS, ORGANIC was see PHOSPHORUS POISONS, ORGANIC 1963-64 (PHOSPHORUS POISONS, ORGANIC deleted 1965)
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of isa	http://purl.bioontology.org/ontology/MESH/D008799 http://purl.bioontology.org/ontology/MESH/C497146 http://purl.bioontology.org/ontology/MESH/C044937 http://purl.bioontology.org/ontology/MESH/D008724 http://purl.bioontology.org/ontology/MESH/D010830 http://purl.bioontology.org/ontology/MESH/D007531 http://purl.bioontology.org/ontology/MESH/D004117 http://purl.bioontology.org/ontology/MESH/C442334 http://purl.bioontology.org/ontology/MESH/D004006 http://purl.bioontology.org/ontology/MESH/D013619 http://purl.bioontology.org/ontology/MESH/D001387 http://purl.bioontology.org/ontology/MESH/D000448 http://purl.bioontology.org/ontology/MESH/D001074 http://purl.bioontology.org/ontology/MESH/D012999 http://purl.bioontology.org/ontology/MESH/C025205 http://purl.bioontology.org/ontology/MESH/D004456 http://purl.bioontology.org/ontology/MESH/D012721 http://purl.bioontology.org/ontology/MESH/C005109 http://purl.bioontology.org/ontology/MESH/D004849 http://purl.bioontology.org/ontology/MESH/D012524 http://purl.bioontology.org/ontology/MESH/C092280 http://purl.bioontology.org/ontology/MESH/C507404 http://purl.bioontology.org/ontology/MESH/D002235 http://purl.bioontology.org/ontology/MESH/C492670 http://purl.bioontology.org/ontology/MESH/D003976 http://purl.bioontology.org/ontology/MESH/C500068 http://purl.bioontology.org/ontology/MESH/D004397 http://purl.bioontology.org/ontology/MESH/D004390 http://purl.bioontology.org/ontology/MESH/C044387 http://purl.bioontology.org/ontology/MESH/D000068836 http://purl.bioontology.org/ontology/MESH/D002709 http://purl.bioontology.org/ontology/MESH/C475423 http://purl.bioontology.org/ontology/MESH/C009680 http://purl.bioontology.org/ontology/MESH/C050426 http://purl.bioontology.org/ontology/MESH/C500839 http://purl.bioontology.org/ontology/MESH/D003372 http://purl.bioontology.org/ontology/MESH/C495227 http://purl.bioontology.org/ontology/MESH/D005278 http://purl.bioontology.org/ontology/MESH/C498881 http://purl.bioontology.org/ontology/MESH/D013751 http://purl.bioontology.org/ontology/MESH/C039088 http://purl.bioontology.org/ontology/MESH/C003135 http://purl.bioontology.org/ontology/MESH/D013770 http://purl.bioontology.org/ontology/MESH/D010278 http://purl.bioontology.org/ontology/MESH/C056424 http://purl.bioontology.org/ontology/MESH/D010702 http://purl.bioontology.org/ontology/MESH/D010707 http://purl.bioontology.org/ontology/MESH/C009374 http://purl.bioontology.org/ontology/MESH/C507036 http://purl.bioontology.org/ontology/MESH/C002752 http://purl.bioontology.org/ontology/MESH/D008294 http://purl.bioontology.org/ontology/MESH/C484874 http://purl.bioontology.org/ontology/MESH/C003117 http://purl.bioontology.org/ontology/MESH/D009267 http://purl.bioontology.org/ontology/MESH/D008743 http://purl.bioontology.org/ontology/MESH/D008999 http://purl.bioontology.org/ontology/MESH/C005197 http://purl.bioontology.org/ontology/MESH/D001138 http://purl.bioontology.org/ontology/MESH/D010261 http://purl.bioontology.org/ontology/MESH/D004491 http://purl.bioontology.org/ontology/MESH/D005702 http://purl.bioontology.org/ontology/MESH/C410959 http://purl.bioontology.org/ontology/MESH/C100193 http://purl.bioontology.org/ontology/MESH/D009388 http://purl.bioontology.org/ontology/MESH/D011729 http://purl.bioontology.org/ontology/MESH/C487422 http://purl.bioontology.org/ontology/MESH/C011269 http://purl.bioontology.org/ontology/MESH/C084645 http://purl.bioontology.org/ontology/MESH/D000077265 http://purl.bioontology.org/ontology/MESH/D000549 http://purl.bioontology.org/ontology/MESH/C503163 http://purl.bioontology.org/ontology/MESH/C503164 http://purl.bioontology.org/ontology/MESH/D005284 http://purl.bioontology.org/ontology/MESH/D014236 http://purl.bioontology.org/ontology/MESH/C052450 http://purl.bioontology.org/ontology/MESH/C008705
Inverse of RB	0
Inverse of RO	http://purl.bioontology.org/ontology/MESH/D008916 http://purl.bioontology.org/ontology/MESH/D009943 http://purl.bioontology.org/ontology/MESH/D010277 http://purl.bioontology.org/ontology/MESH/D007306
Machine permutation	65; CHOLINESTERASE INHIBITORS, IRREVERSIBLE & CHOLINESTERASE INHIBITORS, REVERSIBLE were see under CHOLINESTERASE INHIBITORS 1975-83; CHOLINESTERASE INHIBITORS, ORGANIC was see PHOSPHORUS POISONS, ORGANIC 1963-64 (PHOSPHORUS POISONS, ORGANIC deleted 1965)
MDA	19990101
MMR	20200527
MN	D27.505.519.389.275 D27.505.519.625.120.300 D27.505.696.577.120.300
notation	D002800
OL	use CHOLINESTERASE INHIBITORS to search CHOLINESTERASE INHIBITORS, IRREVERSIBLE & CHOLINESTERASE INHIBITORS, REVERSIBLE 1971-83 (as Prov 1971-74)
prefLabel	Cholinesterase Inhibitors
TERMUI	T000996486 T008160 T008162 T008156 T008161 T008157 T000998054 T000998051 T000998053 T000996391 T000996435 T008158 T008163 T008159
TH	NLM (1996) NLM (1965) NLM (1995) UNK (19XX) NLM (2021)
tui	T109 T121
subClassOf	http://purl.bioontology.org/ontology/MESH/D004791 http://purl.bioontology.org/ontology/MESH/D018678

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/MSHFRE/D002800	MSHFRE	CUI
http://purl.bioontology.org/ontology/MSHFRE/D002800	MSHFRE	CUI
http://purl.bioontology.org/ontology/SCTSPA/771384007	SCTSPA	CUI
http://purl.bioontology.org/ontology/RCD/x01DF	RCD	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/771384007	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/MSHFRE/D002800	MSHFRE	CUI
http://purl.bioontology.org/ontology/ATC/N07AA	ATC	CUI
http://purl.bioontology.org/ontology/MSHFRE/D002800	MSHFRE	CUI
http://purl.bioontology.org/ontology/SNMI/C-67104	SNMI	CUI
http://purl.bioontology.org/ontology/CSP/1038-6721	CRISP	CUI
http://purl.obolibrary.org/obo/MESH_D002800	BERO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D27.505.696.577.120.300	RH-MESH	LOOM
http://doe-generated-ontology.com/OntoAD#C0008425	ONTOAD	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0008425	OCHV	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D27.505.519.625.120.300	RH-MESH	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#2894	OCHV	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00024573	PMAPP-PMO	LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Cholinesterase_Inhibitors	APAONTO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D27.505.519.389.275	RH-MESH	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D002800	RH-MESH	LOOM
http://purl.obolibrary.org/obo/OMIT_0004120	OMIT	LOOM
http://localhost/plosthes.2017-1#4109	PLOSTHES	LOOM