loading...| Preferred Name |
Denosumab |
|
| Synonyms |
AMG 162 |
|
| Definitions |
A humanized monoclonal antibody and an inhibitor of the RANK LIGAND, which regulates OSTEOCLAST differentiation and bone remodeling. It is used as a BONE DENSITY CONSERVATION AGENT in the treatment of OSTEOPOROSIS. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D000069448 |
|
| altLabel |
AMG 162 Prolia Xgeva |
|
| AQL |
AD AE AN BI BL CF CH CL DE EC GE HI IM IP ME PD PH PK PO RE TO TU UL UR |
|
| cui |
C2917754 C1530450 C1690432 C2949325 |
|
| DC |
1 |
|
| definition |
A humanized monoclonal antibody and an inhibitor of the RANK LIGAND, which regulates OSTEOCLAST differentiation and bone remodeling. It is used as a BONE DENSITY CONSERVATION AGENT in the treatment of OSTEOPOROSIS. |
|
| DX |
20160101 |
|
| FX |
D053245 |
|
| HN |
2016 (2004) |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 |
|
| Inverse of RB |
4EQZ6YO2HI 0 |
|
| Inverse of RO | ||
| isa | ||
| LT |
TRD |
|
| Machine permutation |
2016; DENOSUMAB was indexed under ANTIBODIES, MONOCLONAL, HUMANIZED 2012-2015; and under ANTIBODIES, MONOCLONAL 2004-2012 |
|
| MDA |
20150701 |
|
| MMR |
20170620 |
|
| MN |
D12.776.124.486.485.114.224.060.782 D12.776.124.790.651.114.224.060.782 D12.776.377.715.548.114.224.200.782 |
|
| notation |
D000069448 |
|
| PA |
D050071 |
|
| prefLabel |
Denosumab |
|
| RR |
615258-40-7 (denosumab) |
|
| TERMUI |
T625826 T788425 T000880008 T786069 |
|
| TH |
NLM (2004) FDA SRS (2013) NLM (2012) USAN (19XX) INN (19XX) NLM (2006) NLM (2011) |
|
| tui |
T116 T129 T121 |
|
| subClassOf |