loading...| Preferred Name |
Leukemia, Large Granular Lymphocytic |
|
| Synonyms |
Leukemias, NK-LGL |
|
| Definitions |
A spectrum of disorders characterized by clonal expansions of the peripheral blood LYMPHOCYTE populations known as large granular lymphocytes which contain abundant cytoplasm and azurophilic granules. Subtypes develop from either CD3-negative NATURAL KILLER CELLS or CD3-positive T-CELLS. The clinical course of both subtypes can vary from spontaneous regression to progressive, malignant disease. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D054066 |
|
| altLabel |
Leukemias, NK-LGL NK-Cell Large Granular Lymphocytic Leukemia Leukemias, T-LGL LGL Leukemia Leukemia, NK LGL Lymphoproliferative Disease of Large Granular Lymphocytes Leukemia, T-LGL LGL Leukemias Leukemia, T Cell Large Granular Lymphocytic NK LGL Leukemia Leukemia, Lymphocytic, Large Granular T-LGL Leukemia T-Cell Large Granular Lymphocytic Leukemia Leukemia, LGL Lymphocytosis, Large Granular Large Granular Lymphocytoses Lymphocytoses, Large Granular Natural Killer Cell Large Granular Lymphocytic Leukemia Aggressive NK Cell Leukemia Granular Lymphocytoses, Large T Cell Large Granular Lymphocyte Leukemia Leukemia, T LGL Leukemia, Natural Killer Cell Large Granular Lymphocytic Large Granular Lymphocyte Leukemia Leukemia, T-Cell Large Granular Lymphocytic Leukemia, NK-LGL T Cell Large Granular Lymphocytic Leukemia Granular Lymphocytosis, Large NK Cell Large Granular Lymphocytic Leukemia NK-LGL Leukemias Leukemias, LGL T-LGL Leukemias Lymphoproliferative Disease of Granular Lymphocytes T LGL Leukemia T-Cell Large Granular Lymphocyte Leukemia Aggressive Natural Killer Cell Leukemia Large Granular Lymphocytosis NK-LGL Leukemia |
|
| AQL |
BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI |
|
| cui |
C1955860 C1522378 C1955861 |
|
| DC |
1 |
|
| definition |
A spectrum of disorders characterized by clonal expansions of the peripheral blood LYMPHOCYTE populations known as large granular lymphocytes which contain abundant cytoplasm and azurophilic granules. Subtypes develop from either CD3-negative NATURAL KILLER CELLS or CD3-positive T-CELLS. The clinical course of both subtypes can vary from spontaneous regression to progressive, malignant disease. |
|
| DX |
20080101 |
|
| FX |
D008218 |
|
| HN |
2008; use LEUKEMIA, LYMPHOCYTIC 1997-2007 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000178 http://purl.bioontology.org/ontology/MESH/Q000175 http://purl.bioontology.org/ontology/MESH/Q000628 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000139 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000517 http://purl.bioontology.org/ontology/MESH/Q000662 http://purl.bioontology.org/ontology/MESH/Q000469 http://purl.bioontology.org/ontology/MESH/Q000151 http://purl.bioontology.org/ontology/MESH/Q000150 http://purl.bioontology.org/ontology/MESH/Q000821 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000196 http://purl.bioontology.org/ontology/MESH/Q000473 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000382 http://purl.bioontology.org/ontology/MESH/Q000451 http://purl.bioontology.org/ontology/MESH/Q000453 http://purl.bioontology.org/ontology/MESH/Q000534 http://purl.bioontology.org/ontology/MESH/Q000532 http://purl.bioontology.org/ontology/MESH/Q000503 http://purl.bioontology.org/ontology/MESH/Q000188 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000201 http://purl.bioontology.org/ontology/MESH/Q000209 http://purl.bioontology.org/ontology/MESH/Q000208 http://purl.bioontology.org/ontology/MESH/Q000601 http://purl.bioontology.org/ontology/MESH/Q000000981 http://purl.bioontology.org/ontology/MESH/Q000652 |
|
| Inverse of RO | ||
| Machine permutation |
2008; see LEUKEMIA, LYMPHOCYTIC 1997-2007 |
|
| MDA |
20070709 |
|
| MMR |
20230531 |
|
| MN |
C15.604.515.560.575.049 C04.557.337.428.580.049 C20.683.515.528.582.049 C15.378.508.428.580.049 |
|
| notation |
D054066 |
|
| prefLabel |
Leukemia, Large Granular Lymphocytic |
|
| TERMUI |
T679702 T749770 T679707 T679712 T679710 T000879213 T679703 T749769 T679711 T679706 T000880186 T679709 T023666 T679705 T679714 T679713 T679704 T000880185 T023665 T679708 |
|
| TH |
NLM (1997) NLM (2016) NLM (2008) NLM (2010) ORD (2010) |
|
| tui |
T191 |
|
| subClassOf |