loading...| Preferred Name |
Genes, BRCA2 |
|
| Synonyms |
Gene, BRCA2 |
|
| Definitions |
A tumor suppressor gene (GENES, TUMOR SUPPRESSOR) located on human chromosome 13 at locus 13q12.3. Mutations in this gene predispose humans to breast and ovarian cancer. It encodes a large, nuclear protein that is an essential component of DNA repair pathways, suppressing the formation of gross chromosomal rearrangements. (from Genes Dev 2000;14(11):1400-6) |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D024522 |
|
| altLabel |
Gene, BRCA2 BRCA2 Genes BRCA2 Gene |
|
| AN |
BRCA stands for "BReast CAncer" |
|
| AQL |
DE ES PH RE |
|
| cui |
C0598034 |
|
| DC |
1 |
|
| definition |
A tumor suppressor gene (GENES, TUMOR SUPPRESSOR) located on human chromosome 13 at locus 13q12.3. Mutations in this gene predispose humans to breast and ovarian cancer. It encodes a large, nuclear protein that is an essential component of DNA repair pathways, suppressing the formation of gross chromosomal rearrangements. (from Genes Dev 2000;14(11):1400-6) |
|
| DX |
20020101 |
|
| FX |
D024682 |
|
| HN |
2002 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000941 http://purl.bioontology.org/ontology/MESH/Q000502 |
|
| Inverse of RO | ||
| Machine permutation |
2002 |
|
| MDA |
20010725 |
|
| MMR |
20080708 |
|
| MN |
G05.360.340.024.340.415.400.105 G05.360.340.024.340.375.249.105 |
|
| notation |
D024522 |
|
| prefLabel |
Genes, BRCA2 |
|
| TERMUI |
T426847 T425873 |
|
| TH |
NLM (2002) |
|
| tui |
T028 |
|
| subClassOf |