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Last uploaded: January 31, 2024

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Preferred Name	Calcium Channels, L-Type
Synonyms	Dihydropyridine Receptor L Type Calcium Channels Calcium Channel, Long-Lasting Long-Lasting Calcium Channels L Type VDCC L-Type VDCC gamma Subunit L Type VDCC gamma Subunit Receptors, Dihydropyridine Channel, Long-Lasting Calcium Calcium Channel, L-Type Dihydropyridine Receptors L-Type VDCC alpha-1 Subunit L Type Voltage Dependent Calcium Channel Long-Lasting Calcium Channel Calcium Channels, Long-Lasting Calcium Channels, L Type L-Type VDCC delta Subunit L Type VDCC beta Subunit L-Type Voltage-Dependent Calcium Channel L Type Calcium Channel L-Type VDCC Long Lasting Calcium Channels L-Type VDCC beta Subunit Long Lasting Calcium Channel L-Type Calcium Channel L Type Voltage Dependent Calcium Channels L-Type Calcium Channels VDCC, L-Type L Type VDCC alpha 2 Subunit L-Type VDCC alpha-2 Subunit L-Type Voltage-Dependent Calcium Channels L Type VDCC delta Subunit Receptor, Dihydropyridine L Type VDCC alpha 1 Subunit
Definitions	Long-lasting voltage-gated CALCIUM CHANNELS found in both excitable and non-excitable tissue. They are responsible for normal myocardial and vascular smooth muscle contractility. Five subunits (alpha-1, alpha-2, beta, gamma, and delta) make up the L-type channel. The alpha-1 subunit is the binding site for calcium-based antagonists. Dihydropyridine-based calcium antagonists are used as markers for these binding sites.
ID	http://purl.bioontology.org/ontology/MESH/D020746
altLabel	Dihydropyridine Receptor L Type Calcium Channels Calcium Channel, Long-Lasting Long-Lasting Calcium Channels L Type VDCC L-Type VDCC gamma Subunit L Type VDCC gamma Subunit Receptors, Dihydropyridine Channel, Long-Lasting Calcium Calcium Channel, L-Type Dihydropyridine Receptors L-Type VDCC alpha-1 Subunit L Type Voltage Dependent Calcium Channel Long-Lasting Calcium Channel Calcium Channels, Long-Lasting Calcium Channels, L Type L-Type VDCC delta Subunit L Type VDCC beta Subunit L-Type Voltage-Dependent Calcium Channel L Type Calcium Channel L-Type VDCC Long Lasting Calcium Channels L-Type VDCC beta Subunit Long Lasting Calcium Channel L-Type Calcium Channel L Type Voltage Dependent Calcium Channels L-Type Calcium Channels VDCC, L-Type L Type VDCC alpha 2 Subunit L-Type VDCC alpha-2 Subunit L-Type Voltage-Dependent Calcium Channels L Type VDCC delta Subunit Receptor, Dihydropyridine L Type VDCC alpha 1 Subunit
AQL	AD AE AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
cui	C0752116 C0752115 C0288263 C0752114 C0752113 C0218111
DC	1
definition	Long-lasting voltage-gated CALCIUM CHANNELS found in both excitable and non-excitable tissue. They are responsible for normal myocardial and vascular smooth muscle contractility. Five subunits (alpha-1, alpha-2, beta, gamma, and delta) make up the L-type channel. The alpha-1 subunit is the binding site for calcium-based antagonists. Dihydropyridine-based calcium antagonists are used as markers for these binding sites.
DX	20000101
HN	2000; use L-TYPE CALCIUM CHANNELS (NM) 1993-1999
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	0
Machine permutation	2000; DIHYDROPYRIDINE RECEPTOR (now L-TYPE CALCIUM CHANNELS) was indexed under CALCIUM CHANNELS & MUSCLE PROTEINS 1993-1999
Mapped from	http://purl.bioontology.org/ontology/MESH/C079146 http://purl.bioontology.org/ontology/MESH/C529218 http://purl.bioontology.org/ontology/MESH/C485995 http://purl.bioontology.org/ontology/MESH/C514350 http://purl.bioontology.org/ontology/MESH/C509902 http://purl.bioontology.org/ontology/MESH/C504728 http://purl.bioontology.org/ontology/MESH/C491527 http://purl.bioontology.org/ontology/MESH/C491528 http://purl.bioontology.org/ontology/MESH/C107597 http://purl.bioontology.org/ontology/MESH/C486060 http://purl.bioontology.org/ontology/MESH/C492923 http://purl.bioontology.org/ontology/MESH/C113330 http://purl.bioontology.org/ontology/MESH/C580633 http://purl.bioontology.org/ontology/MESH/C512890 http://purl.bioontology.org/ontology/MESH/C000595452 http://purl.bioontology.org/ontology/MESH/C472073 http://purl.bioontology.org/ontology/MESH/C480684 http://purl.bioontology.org/ontology/MESH/C412223 http://purl.bioontology.org/ontology/MESH/C577848 http://purl.bioontology.org/ontology/MESH/C498838 http://purl.bioontology.org/ontology/MESH/C480737 http://purl.bioontology.org/ontology/MESH/C419385 http://purl.bioontology.org/ontology/MESH/C488619 http://purl.bioontology.org/ontology/MESH/C493217
MDA	19991104
MMR	20210630
MN	D12.776.157.530.400.150.400 D12.776.543.585.400.150.400 D12.776.543.550.450.150.400
notation	D020746
prefLabel	Calcium Channels, L-Type
TERMUI	T248987 T364749 T364750 T365024 T248988 T000997832 T248986 T365025 T358046 T373129 T364753 T000997833 T365023 T364752 T248989 T364751
TH	NLM (2000) NLM (2021)
tui	T116 T123
subClassOf	http://purl.bioontology.org/ontology/MESH/D015220

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/MSHFRE/D020746	MSHFRE	CUI
http://purl.bioontology.org/ontology/MSHFRE/D020746	MSHFRE	CUI
http://purl.bioontology.org/ontology/MSHFRE/D020746	MSHFRE	CUI
http://purl.bioontology.org/ontology/MSHFRE/D020746	MSHFRE	CUI
http://purl.bioontology.org/ontology/MSHFRE/D020746	MSHFRE	CUI
http://purl.bioontology.org/ontology/MSHFRE/D020746	MSHFRE	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000169747	NDFRT	CUI
http://purl.bioontology.org/ontology/CSP/2447-6400	CRISP	CUI
http://purl.obolibrary.org/obo/MESH_D020746	BERO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.157.530.400.150.400	RH-MESH	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.543.550.425.150.400	RH-MESH	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00022352	PMAPP-PMO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.543.585.400.150.400	RH-MESH	LOOM
http://purl.jp/bio/4/id/200906074020801484	IOBC	LOOM
http://purl.obolibrary.org/obo/OMIT_0020594	OMIT	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D020746	RH-MESH	LOOM