loading...| Preferred Name |
Ryanodine Receptor Calcium Release Channel |
|
| Synonyms |
Receptor 3, Ryanodine Receptors, Ryanodine RyR2 Receptor Complex, Calcium-Ryanodine Ryanodine Receptor Ryanodine Receptor 3 Ca Release Channel Ryanodine Receptor Receptor, Ryanodine Ca Release Channel-Ryanodine Receptor Complex, Calcium-Ryanodine Receptor Ryanodine Receptor 1 Calcium-Ryanodine Receptor Complex Calcium Ryanodine Receptor Complex Ryanodine Receptors RyR3 Ryanodine Receptor 2 RyR1 Receptor 1, Ryanodine Receptor 2, Ryanodine |
|
| Definitions |
A tetrameric calcium release channel in the SARCOPLASMIC RETICULUM membrane of SMOOTH MUSCLE CELLS, acting oppositely to SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES. It is important in skeletal and cardiac excitation-contraction coupling and studied by using RYANODINE. Abnormalities are implicated in CARDIAC ARRHYTHMIAS and MUSCULAR DISEASES. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D019837 |
|
| altLabel |
Receptor 3, Ryanodine Receptors, Ryanodine RyR2 Receptor Complex, Calcium-Ryanodine Ryanodine Receptor Ryanodine Receptor 3 Ca Release Channel Ryanodine Receptor Receptor, Ryanodine Ca Release Channel-Ryanodine Receptor Complex, Calcium-Ryanodine Receptor Ryanodine Receptor 1 Calcium-Ryanodine Receptor Complex Calcium Ryanodine Receptor Complex Ryanodine Receptors RyR3 Ryanodine Receptor 2 RyR1 Receptor 1, Ryanodine Receptor 2, Ryanodine |
|
| AQL |
AD AE AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR |
|
| cui |
C0054493 C0524964 C0524965 C0917729 C0524963 |
|
| DC |
1 |
|
| definition |
A tetrameric calcium release channel in the SARCOPLASMIC RETICULUM membrane of SMOOTH MUSCLE CELLS, acting oppositely to SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES. It is important in skeletal and cardiac excitation-contraction coupling and studied by using RYANODINE. Abnormalities are implicated in CARDIAC ARRHYTHMIAS and MUSCULAR DISEASES. |
|
| DX |
19980101 |
|
| EC |
antagonists & inhibitors:Calcium Channel Blockers agonists:Calcium Channel Agonists |
|
| HN |
98; use RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL (NM) 1985-97 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
0 |
|
| Machine permutation |
98; CALCIUM-RYANODINE RECEPTOR COMPLEX (now RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL) was indexed under CALCIUM CHANNELS 1988-97, MUSCLE PROTEINS 1993-97, & RECEPTORS, CHOLINERGIC 1985-92 |
|
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C000592747 http://purl.bioontology.org/ontology/MESH/C564969 http://purl.bioontology.org/ontology/MESH/C000612605 http://purl.bioontology.org/ontology/MESH/C451408 http://purl.bioontology.org/ontology/MESH/C451409 http://purl.bioontology.org/ontology/MESH/C438601 http://purl.bioontology.org/ontology/MESH/C000621072 http://purl.bioontology.org/ontology/MESH/C000655325 http://purl.bioontology.org/ontology/MESH/C000629268 |
|
| MDA |
19970620 |
|
| MMR |
20160701 |
|
| MN |
D12.776.210.500.800 D12.776.543.585.400.150.800 D12.776.543.550.450.150.800 D12.776.157.530.400.150.800 |
|
| notation |
D019837 |
|
| prefLabel |
Ryanodine Receptor Calcium Release Channel |
|
| TERMUI |
T721527 T059030 T059023 T059022 T059027 T059024 T059029 T721526 T059026 T059028 T721528 T059025 |
|
| TH |
NLM (2009) NLM (1998) |
|
| tui |
T116 T192 |
|
| subClassOf |