loading...| Preferred Name |
Genes, erbB-1 |
|
| Synonyms |
c-erbB-1 Genes c erbB 1 Proto Oncogenes v-erbB Gene Genes, erbB1 c-erbB-1 Gene Epidermal Growth Factor Receptor Genes Gene, erbB1 c erbB 1 Genes v-erbB Oncogenes v erbB Genes c-erbB-1 Proto-Oncogenes erbB1 Genes v erbB Oncogenes erbB 1 Genes c-erbB-1 Proto-Oncogene Genes, EGFR erbB-1 Gene EGFR Gene erbB1 Gene v-erbB Oncogene v-erbB Genes EGFR Genes erbB-1 Genes |
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| Definitions |
The proto-oncogene c-erbB-1 codes for the epidermal growth factor receptor. Its name originates from the viral homolog v-erbB which was isolated from an avian erythroblastosis virus (AEV) where it was contained as a fragment of the chicken c-ErbB-1 gene lacking the amino-terminal ligand-binding domain. Overexpression of erbB-1 genes occurs in a wide range of tumors, commonly squamous carcinomas of various sites and less commonly adenocarcinomas. The human c-erbB-1 gene is located in the chromosomal region 7p14 and 7p12. |
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| ID |
http://purl.bioontology.org/ontology/MESH/D018773 |
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| altLabel |
c-erbB-1 Genes c erbB 1 Proto Oncogenes v-erbB Gene Genes, erbB1 c-erbB-1 Gene Epidermal Growth Factor Receptor Genes Gene, erbB1 c erbB 1 Genes v-erbB Oncogenes v erbB Genes c-erbB-1 Proto-Oncogenes erbB1 Genes v erbB Oncogenes erbB 1 Genes c-erbB-1 Proto-Oncogene Genes, EGFR erbB-1 Gene EGFR Gene erbB1 Gene v-erbB Oncogene v-erbB Genes EGFR Genes erbB-1 Genes |
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| AN |
spell in titles & translations as erbB-1; GENES, ERBB-2 is also available |
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| AQL |
DE ES GE IM PH RE |
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| cui |
C0242983 C0242984 C0242982 |
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| DC |
1 |
|
| definition |
The proto-oncogene c-erbB-1 codes for the epidermal growth factor receptor. Its name originates from the viral homolog v-erbB which was isolated from an avian erythroblastosis virus (AEV) where it was contained as a fragment of the chicken c-ErbB-1 gene lacking the amino-terminal ligand-binding domain. Overexpression of erbB-1 genes occurs in a wide range of tumors, commonly squamous carcinomas of various sites and less commonly adenocarcinomas. The human c-erbB-1 gene is located in the chromosomal region 7p14 and 7p12. |
|
| DX |
19950101 |
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| FX |
D066246 D018739 |
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| HN |
1995 |
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| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000941 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000187 |
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| Inverse of RO | ||
| Machine permutation |
1995 |
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| MDA |
19940523 |
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| MMR |
20180702 |
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| MN |
G05.360.340.024.340.375.500.791.295.300 |
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| notation |
D018773 |
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| prefLabel |
Genes, erbB-1 |
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| TERMUI |
T373109 T362164 T055898 T055901 T055900 T362163 T055896 T055899 T055897 T055895 |
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| TH |
NLM (2000) NLM (1995) |
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| tui |
T028 |
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| subClassOf |