Medical Subject Headings

Last uploaded: January 31, 2024
Preferred Name

Negative Staining

Synonyms

Staining, Negative

Definitions

The technique of washing tissue specimens with a concentrated solution of a heavy metal salt and letting it dry. The specimen will be covered with a very thin layer of the metal salt, being excluded in areas where an adsorbed macromolecule is present. The macromolecules allow electrons from the beam of an electron microscope to pass much more readily than the heavy metal; thus, a reversed or negative image of the molecule is created.

ID

http://purl.bioontology.org/ontology/MESH/D016624

altLabel

Staining, Negative

AQL

CL EC ES HI IS MT SN ST TD VE

cui

C0085194

DC

1

definition

The technique of washing tissue specimens with a concentrated solution of a heavy metal salt and letting it dry. The specimen will be covered with a very thin layer of the metal salt, being excluded in areas where an adsorbed macromolecule is present. The macromolecules allow electrons from the beam of an electron microscope to pass much more readily than the heavy metal; thus, a reversed or negative image of the molecule is created.

DX

19920101

HN

92

Inverse of AQ

http://purl.bioontology.org/ontology/MESH/Q000266

http://purl.bioontology.org/ontology/MESH/Q000379

http://purl.bioontology.org/ontology/MESH/Q000706

http://purl.bioontology.org/ontology/MESH/Q000662

http://purl.bioontology.org/ontology/MESH/Q000941

http://purl.bioontology.org/ontology/MESH/Q000191

http://purl.bioontology.org/ontology/MESH/Q000145

http://purl.bioontology.org/ontology/MESH/Q000592

http://purl.bioontology.org/ontology/MESH/Q000295

http://purl.bioontology.org/ontology/MESH/Q000639

Machine permutation

92

MDA

19910125

MMR

20110624

MN

E05.200.750.600.670.520

E01.370.225.750.600.670.520

E01.370.225.500.620.670.520

E05.200.500.620.670.520

notation

D016624

prefLabel

Negative Staining

TERMUI

T049769

TH

NLM (1992)

tui

T059

subClassOf

http://purl.bioontology.org/ontology/MESH/D013194

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