Preferred Name |
Negative Staining |
|
Synonyms |
Staining, Negative |
|
Definitions |
The technique of washing tissue specimens with a concentrated solution of a heavy metal salt and letting it dry. The specimen will be covered with a very thin layer of the metal salt, being excluded in areas where an adsorbed macromolecule is present. The macromolecules allow electrons from the beam of an electron microscope to pass much more readily than the heavy metal; thus, a reversed or negative image of the molecule is created. |
|
ID |
http://purl.bioontology.org/ontology/MESH/D016624 |
|
altLabel |
Staining, Negative |
|
AQL |
CL EC ES HI IS MT SN ST TD VE |
|
cui |
C0085194 |
|
DC |
1 |
|
definition |
The technique of washing tissue specimens with a concentrated solution of a heavy metal salt and letting it dry. The specimen will be covered with a very thin layer of the metal salt, being excluded in areas where an adsorbed macromolecule is present. The macromolecules allow electrons from the beam of an electron microscope to pass much more readily than the heavy metal; thus, a reversed or negative image of the molecule is created. |
|
DX |
19920101 |
|
HN |
92 |
|
Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000379 http://purl.bioontology.org/ontology/MESH/Q000706 http://purl.bioontology.org/ontology/MESH/Q000662 http://purl.bioontology.org/ontology/MESH/Q000941 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 |
|
Machine permutation |
92 |
|
MDA |
19910125 |
|
MMR |
20110624 |
|
MN |
E05.200.750.600.670.520 E01.370.225.750.600.670.520 E01.370.225.500.620.670.520 E05.200.500.620.670.520 |
|
notation |
D016624 |
|
prefLabel |
Negative Staining |
|
TERMUI |
T049769 |
|
TH |
NLM (1992) |
|
tui |
T059 |
|
subClassOf |