A glycoprotein of MW 25 kDa containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines.
ID
http://purl.bioontology.org/ontology/MESH/D016179
altLabel
G-CSF
Colony Stimulating Factor, Granulocyte
Factor, Granulocyte Colony-Stimulating
Myeloid Growth Factor
Growth Factor, Myeloid
Factor, Myeloid Growth
Colony-Stimulating Factor, Granulocyte
Granulocyte Colony Stimulating Factor
AQL
AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
cui
C0079459
DC
1
definition
A glycoprotein of MW 25 kDa containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines.
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