Medical Subject Headings

Last uploaded: January 31, 2024

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Preferred Name	Vinca Alkaloids
Synonyms	Alkaloids, Vinca
Definitions	A group of indole-indoline dimers which are ALKALOIDS obtained from the VINCA genus of plants. They inhibit polymerization of TUBULIN into MICROTUBULES thus blocking spindle formation and arresting cells in METAPHASE. They are some of the most useful ANTINEOPLASTIC AGENTS.
ID	http://purl.bioontology.org/ontology/MESH/D014748
altLabel	Alkaloids, Vinca
AQL	AD AE AG AI AN BI BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
cui	C0042672
DC	1
definition	A group of indole-indoline dimers which are ALKALOIDS obtained from the VINCA genus of plants. They inhibit polymerization of TUBULIN into MICROTUBULES thus blocking spindle formation and arresting cells in METAPHASE. They are some of the most useful ANTINEOPLASTIC AGENTS.
DX	19730101
HN	73
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	0
isa	http://purl.bioontology.org/ontology/MESH/D000970 http://purl.bioontology.org/ontology/MESH/D050257
Machine permutation	73
Mapped from	http://purl.bioontology.org/ontology/MESH/C010318 http://purl.bioontology.org/ontology/MESH/C044935 http://purl.bioontology.org/ontology/MESH/C434289 http://purl.bioontology.org/ontology/MESH/C013983 http://purl.bioontology.org/ontology/MESH/C520389 http://purl.bioontology.org/ontology/MESH/C026089 http://purl.bioontology.org/ontology/MESH/C016463 http://purl.bioontology.org/ontology/MESH/C500660 http://purl.bioontology.org/ontology/MESH/C057240 http://purl.bioontology.org/ontology/MESH/C088124 http://purl.bioontology.org/ontology/MESH/C065619 http://purl.bioontology.org/ontology/MESH/C075611 http://purl.bioontology.org/ontology/MESH/C032858 http://purl.bioontology.org/ontology/MESH/C032859 http://purl.bioontology.org/ontology/MESH/C010181 http://purl.bioontology.org/ontology/MESH/C532690 http://purl.bioontology.org/ontology/MESH/C038627 http://purl.bioontology.org/ontology/MESH/C511649 http://purl.bioontology.org/ontology/MESH/C519604 http://purl.bioontology.org/ontology/MESH/C017836 http://purl.bioontology.org/ontology/MESH/C556242 http://purl.bioontology.org/ontology/MESH/C016092 http://purl.bioontology.org/ontology/MESH/C408672 http://purl.bioontology.org/ontology/MESH/C027649 http://purl.bioontology.org/ontology/MESH/C021093 http://purl.bioontology.org/ontology/MESH/C064005 http://purl.bioontology.org/ontology/MESH/C016422 http://purl.bioontology.org/ontology/MESH/C516363 http://purl.bioontology.org/ontology/MESH/C099167 http://purl.bioontology.org/ontology/MESH/C571794 http://purl.bioontology.org/ontology/MESH/C543267 http://purl.bioontology.org/ontology/MESH/C002067 http://purl.bioontology.org/ontology/MESH/C059426 http://purl.bioontology.org/ontology/MESH/C042392 http://purl.bioontology.org/ontology/MESH/C039296 http://purl.bioontology.org/ontology/MESH/C039298 http://purl.bioontology.org/ontology/MESH/C039297 http://purl.bioontology.org/ontology/MESH/C528499 http://purl.bioontology.org/ontology/MESH/C054727 http://purl.bioontology.org/ontology/MESH/C539462 http://purl.bioontology.org/ontology/MESH/C035286 http://purl.bioontology.org/ontology/MESH/C081044 http://purl.bioontology.org/ontology/MESH/C107224
MDA	19990101
MMR	20200527
MN	D03.633.100.496.500.500.681.827 D03.132.436.681.827 D03.633.100.473.402.681.827
notation	D014748
PA	D000970 D050257
prefLabel	Vinca Alkaloids
TERMUI	T043092
TH	NLM (1973)
tui	T109 T121
subClassOf	http://purl.bioontology.org/ontology/MESH/D046948

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/RCD/x01Ai	RCD	CUI
http://purl.bioontology.org/ontology/MSHFRE/D014748	MSHFRE	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000007780	NDFRT	CUI
http://purl.bioontology.org/ontology/CSP/0093-3505	CRISP	CUI
http://purl.bioontology.org/ontology/SNMI/C-30396	SNMI	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/61864009	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/SCTSPA/61864009	SCTSPA	CUI
http://purl.obolibrary.org/obo/OMIT_0015579	OMIT	LOOM
http://id.nlm.nih.gov/mesh/D014748	MDM	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.132.436.681.827	RH-MESH	LOOM
http://doe-generated-ontology.com/OntoAD#C0042672	ONTOAD	LOOM
http://purl.obolibrary.org/obo/MESH_D014748	BERO	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#12998	OCHV	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D014748	RH-MESH	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017734	PMAPP-PMO	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0042672	OCHV	LOOM
http://purl.jp/bio/4/id/200906036358241175	IOBC	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.473.402.681.827	RH-MESH	LOOM