loading...| Preferred Name |
Tetanus Toxin |
|
| Synonyms |
Tetanus Toxins |
|
| Definitions |
Protein synthesized by CLOSTRIDIUM TETANI as a single chain of ~150 kDa with 35% sequence identity to BOTULINUM TOXIN that is cleaved to a light and a heavy chain that are linked by a single disulfide bond. Tetanolysin is the hemolytic and tetanospasmin is the neurotoxic principle. The toxin causes disruption of the inhibitory mechanisms of the CNS, thus permitting uncontrolled nervous activity, leading to fatal CONVULSIONS. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D013744 |
|
| altLabel |
Tetanus Toxins Toxin, Clostridium tetani Clostridium tetani Toxin Clostridial Neurotoxin Toxins, Tetanus Neurotoxin, Clostridial Toxin, Tetanus |
|
| AN |
/antag permitted but consider also TETANUS ANTITOXIN |
|
| AQL |
AD AE AG AI AN BI BL CF CH CL CS EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UR |
|
| cui |
C0039617 C0086023 |
|
| DC |
1 |
|
| definition |
Protein synthesized by CLOSTRIDIUM TETANI as a single chain of ~150 kDa with 35% sequence identity to BOTULINUM TOXIN that is cleaved to a light and a heavy chain that are linked by a single disulfide bond. Tetanolysin is the hemolytic and tetanospasmin is the neurotoxic principle. The toxin causes disruption of the inhibitory mechanisms of the CNS, thus permitting uncontrolled nervous activity, leading to fatal CONVULSIONS. |
|
| DX |
19650101 |
|
| FX |
D013743 |
|
| HN |
65 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
0 |
|
| Inverse of RO | ||
| isa | ||
| Machine permutation |
65 |
|
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C040635 http://purl.bioontology.org/ontology/MESH/C051903 http://purl.bioontology.org/ontology/MESH/C026167 http://purl.bioontology.org/ontology/MESH/C035979 http://purl.bioontology.org/ontology/MESH/C091828 http://purl.bioontology.org/ontology/MESH/C549316 |
|
| MDA |
19990101 |
|
| MMR |
20200527 |
|
| MN |
D23.946.123.893 D12.776.097.872 |
|
| notation |
D013744 |
|
| PA |
D009498 |
|
| prefLabel |
Tetanus Toxin |
|
| TERMUI |
T040365 T040368 T040367 T040366 |
|
| TH |
NLM (1965) UNK (19XX) |
|
| tui |
T116 T131 T121 |
|
| subClassOf |