Medical Subject Headings

Last uploaded: January 31, 2024

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Preferred Name	SRS-A
Synonyms	Slow Reacting Substance of Anaphylaxis
Definitions	A group of LEUKOTRIENES; (LTC4; LTD4; and LTE4) that is the major mediator of BRONCHOCONSTRICTION; HYPERSENSITIVITY; and other allergic reactions. Earlier studies described a "slow-reacting substance of ANAPHYLAXIS" released from lung by cobra venom or after anaphylactic shock. The relationship between SRS-A leukotrienes was established by UV which showed the presence of the conjugated triene. (From Merck Index, 11th ed)
ID	http://purl.bioontology.org/ontology/MESH/D013189
altLabel	Slow Reacting Substance of Anaphylaxis
AN	/biosyn /physiol permitted
AQL	AA AD AE AG AI AN BI BL CF CH CL CS DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UR
cui	C0038091
DC	1
definition	A group of LEUKOTRIENES; (LTC4; LTD4; and LTE4) that is the major mediator of BRONCHOCONSTRICTION; HYPERSENSITIVITY; and other allergic reactions. Earlier studies described a "slow-reacting substance of ANAPHYLAXIS" released from lung by cobra venom or after anaphylactic shock. The relationship between SRS-A leukotrienes was established by UV which showed the presence of the conjugated triene. (From Merck Index, 11th ed)
DX	19730101
HN	73(67)
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	0
Inverse of RO	http://purl.bioontology.org/ontology/MESH/D000707
Machine permutation	73
Mapped from	http://purl.bioontology.org/ontology/MESH/C028724 http://purl.bioontology.org/ontology/MESH/C028725 http://purl.bioontology.org/ontology/MESH/C058160 http://purl.bioontology.org/ontology/MESH/C071435 http://purl.bioontology.org/ontology/MESH/C037113 http://purl.bioontology.org/ontology/MESH/C066221 http://purl.bioontology.org/ontology/MESH/C026144 http://purl.bioontology.org/ontology/MESH/C058840 http://purl.bioontology.org/ontology/MESH/C058841 http://purl.bioontology.org/ontology/MESH/C036173 http://purl.bioontology.org/ontology/MESH/C036175 http://purl.bioontology.org/ontology/MESH/C036174 http://purl.bioontology.org/ontology/MESH/C062039 http://purl.bioontology.org/ontology/MESH/C077266 http://purl.bioontology.org/ontology/MESH/C025492 http://purl.bioontology.org/ontology/MESH/C049906 http://purl.bioontology.org/ontology/MESH/C047680 http://purl.bioontology.org/ontology/MESH/C066047 http://purl.bioontology.org/ontology/MESH/C044701 http://purl.bioontology.org/ontology/MESH/C037150
MDA	19990101
MMR	20150608
MN	D10.251.355.310.166.887.855 D10.251.355.255.100.450.855 D23.469.050.175.450.725
notation	D013189
prefLabel	SRS-A
TERMUI	T038737 T038738
TH	UNK (19XX) NLM (1967)
tui	T109 T123
subClassOf	http://purl.bioontology.org/ontology/MESH/D015289

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/MSHFRE/D013189	MSHFRE	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/34745001	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/SNMI/F-CB020	SNMI	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000171041	NDFRT	CUI
http://purl.bioontology.org/ontology/SCTSPA/34745001	SCTSPA	CUI
http://purl.obolibrary.org/obo/MESH_D013189	BERO	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00021102	PMAPP-PMO	LOOM
http://id.nlm.nih.gov/mesh/D013189	MDM	LOOM
http://purl.obolibrary.org/obo/OMIT_0014067	OMIT	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D10.251.355.255.100.450.855	RH-MESH	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D23.469.050.175.450.725	RH-MESH	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D013189	RH-MESH	LOOM