loading...| Preferred Name |
Hemoglobinuria, Paroxysmal |
|
| Synonyms |
Paroxysmal Nocturnal Hemoglobinuria |
|
| Definitions |
A condition characterized by the recurrence of HEMOGLOBINURIA caused by intravascular HEMOLYSIS. In cases occurring upon cold exposure (paroxysmal cold hemoglobinuria), usually after infections, there is a circulating antibody which is also a cold hemolysin. In cases occurring during or after sleep (paroxysmal nocturnal hemoglobinuria), the clonal hematopoietic stem cells exhibit a global deficiency of cell membrane proteins. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D006457 |
|
| altLabel |
Paroxysmal Nocturnal Hemoglobinuria Paroxysmal Hemoglobinuria, Cold Nocturnal Paroxysmal Hemoglobinuria Marchiafava Micheli Syndrome Hemoglobinuria, Nocturnal Paroxysmal Paroxysmal Cold Hemoglobinuria Marchiafava-Micheli Syndrome Hemoglobinuria, Cold Paroxysmal Syndrome, Marchiafava-Micheli Cold Paroxysmal Hemoglobinuria Paroxysmal Hemoglobinuria, Nocturnal Hemoglobinuria, Paroxysmal Nocturnal Paroxysmal Hemoglobinuria Hemoglobinuria, Paroxysmal Cold |
|
| AQL |
BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI |
|
| cui |
C0086774 C0024790 C0019050 |
|
| DC |
1 |
|
| definition |
A condition characterized by the recurrence of HEMOGLOBINURIA caused by intravascular HEMOLYSIS. In cases occurring upon cold exposure (paroxysmal cold hemoglobinuria), usually after infections, there is a circulating antibody which is also a cold hemolysin. In cases occurring during or after sleep (paroxysmal nocturnal hemoglobinuria), the clonal hematopoietic stem cells exhibit a global deficiency of cell membrane proteins. |
|
| DX |
19780101 |
|
| HN |
78; was MARCHIAFAVA-MICHELI SYNDROME 1963-77 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000178 http://purl.bioontology.org/ontology/MESH/Q000175 http://purl.bioontology.org/ontology/MESH/Q000628 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000139 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000517 http://purl.bioontology.org/ontology/MESH/Q000662 http://purl.bioontology.org/ontology/MESH/Q000469 http://purl.bioontology.org/ontology/MESH/Q000151 http://purl.bioontology.org/ontology/MESH/Q000150 http://purl.bioontology.org/ontology/MESH/Q000821 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000196 http://purl.bioontology.org/ontology/MESH/Q000473 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000382 http://purl.bioontology.org/ontology/MESH/Q000451 http://purl.bioontology.org/ontology/MESH/Q000453 http://purl.bioontology.org/ontology/MESH/Q000534 http://purl.bioontology.org/ontology/MESH/Q000532 http://purl.bioontology.org/ontology/MESH/Q000503 http://purl.bioontology.org/ontology/MESH/Q000188 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000201 http://purl.bioontology.org/ontology/MESH/Q000209 http://purl.bioontology.org/ontology/MESH/Q000208 http://purl.bioontology.org/ontology/MESH/Q000601 http://purl.bioontology.org/ontology/MESH/Q000000981 http://purl.bioontology.org/ontology/MESH/Q000652 |
|
| Machine permutation |
78; was MARCHIAFAVA-MICHELI SYNDROME 1963-77 |
|
| MDA |
19990101 |
|
| MMR |
20230226 |
|
| MN |
C15.378.050.141.560 C15.378.190.625.460 |
|
| notation |
D006457 |
|
| OL |
use HEMOGLOBINURIA, PAROXYSMAL to search MARCHIAFAVA-MICHELI SYNDROME 1966-77 |
|
| prefLabel |
Hemoglobinuria, Paroxysmal |
|
| TERMUI |
T019494 T666933 T019496 T666934 T019495 T666932 T019497 |
|
| TH |
OMIM (2013) NLM (1966) NLM (1992) UNK (19XX) GHR (2014) NLM (2007) ORD (2010) |
|
| tui |
T047 |
|
| subClassOf |