loading...| Preferred Name |
DNA Topoisomerases, Type I |
|
| Synonyms |
DNA Untwisting Protein |
|
| Definitions |
DNA TOPOISOMERASES that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. DNA Topoisomerases, Type I enzymes reduce the topological stress in the DNA structure by relaxing the superhelical turns and knotted rings in the DNA helix. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D004264 |
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| altLabel |
DNA Untwisting Protein Topoisomerase I DNA Untwisting Enzyme DNA topoisomerase IIIalpha, Topoisomerase DNA Relaxing Protein DNA Untwisting Enzymes Topoisomerase IIIbeta Topoisomerase III, DNA DNA Nicking-Closing Proteins III, Topoisomerase IIIbeta, Topoisomerase DNA Topoisomerase III, Topo Type I DNA Topoisomerase DNA Relaxing Enzyme TOPO IIIalpha DNA Untwisting Proteins DNA Relaxing Enzymes DNA Topoisomerase III alpha Topoisomerase III beta Topoisomerase III DNA Topoisomerase III beta DNA Topoisomerase III Topoisomerase, TOP3 DNA Nicking-Closing Protein IIIalpha, TOPO TOP3alpha DNA Topoisomerase I III, DNA Topoisomerase III beta, Topoisomerase beta, Topoisomerase III TOP3 Topoisomerase Topoisomerase IIIalpha DNA Type 1 Topoisomerase Topo III |
|
| AN |
do not confuse entry term DNA UNTWISTING PROTEIN with DNA UNWINDING PROTEINS see DNA HELICASES; coordinate with BACTERIAL PROTEINS or ARCHAEAL PROTEINS if pertinent |
|
| AQL |
AD AE AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR |
|
| cui |
C1336659 C3853929 C0012920 C1172436 |
|
| DC |
1 |
|
| definition |
DNA TOPOISOMERASES that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. DNA Topoisomerases, Type I enzymes reduce the topological stress in the DNA structure by relaxing the superhelical turns and knotted rings in the DNA helix. |
|
| DX |
19780101 |
|
| EC |
antagonists & inhibitors:Topoisomerase I Inhibitors |
|
| HN |
2002 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
EC 5.99.1.2 0 |
|
| Inverse of RO | ||
| Machine permutation |
2002; see DNA TOPOISOMERASE 1994-2001, see DNA UNTWISTING PROTEINS 1978-1993; for DNA NICKING-CLOSING PROTEIN see DNA NICKING-CLOSING PROTEINS 1978-1993; for DNA RELAXING ENZYME see DNA RELAXING ENZYMES 1978-1993; for DNA UNTWISTING ENZYME see DNA UNTWISTING ENZYMES 1978-1993 |
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| Mapped from |
http://purl.bioontology.org/ontology/MESH/C469259 http://purl.bioontology.org/ontology/MESH/C469258 http://purl.bioontology.org/ontology/MESH/C000629910 http://purl.bioontology.org/ontology/MESH/C526975 http://purl.bioontology.org/ontology/MESH/C000629602 http://purl.bioontology.org/ontology/MESH/C475926 http://purl.bioontology.org/ontology/MESH/C054767 http://purl.bioontology.org/ontology/MESH/C082698 http://purl.bioontology.org/ontology/MESH/C528909 http://purl.bioontology.org/ontology/MESH/C041813 http://purl.bioontology.org/ontology/MESH/C000624945 http://purl.bioontology.org/ontology/MESH/C000630581 http://purl.bioontology.org/ontology/MESH/C000630578 http://purl.bioontology.org/ontology/MESH/C000630577 http://purl.bioontology.org/ontology/MESH/C000630579 http://purl.bioontology.org/ontology/MESH/C000629601 http://purl.bioontology.org/ontology/MESH/C000630576 http://purl.bioontology.org/ontology/MESH/C000630580 http://purl.bioontology.org/ontology/MESH/C068026 http://purl.bioontology.org/ontology/MESH/C068025 |
|
| MDA |
19770415 |
|
| MMR |
20190708 |
|
| MN |
D12.776.157.687.375 D08.811.399.403.483 D12.776.660.720.375 |
|
| notation |
D004264 |
|
| prefLabel |
DNA Topoisomerases, Type I |
|
| RR |
143180-75-0 (CAS RN) |
|
| TERMUI |
T000958390 T012969 T000958387 T012972 T000958393 T012965 T000958391 T012970 T000958388 T012961 T000958395 T012963 T000958386 T012964 T000958394 T012962 T012967 T000958389 T012971 T012975 T012968 T000958392 T000958396 T012966 T439293 T012976 |
|
| TH |
NLM (2002) NLM (2020) NLM (1994) NLM (1978) UNK (19XX) |
|
| tui |
T116 T126 T028 |
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| subClassOf |