Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.
ID
http://purl.bioontology.org/ontology/MESH/D003091
altLabel
Sulfate, Colistin
Polymyxin E
Colistin Sulfate
Totazina
Colimycin
Coly-Mycin
Colisticin
AQL
AA AD AE AG AI AN BI BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
cui
C0701961
C0701962
C0009316
C0009317
DC
1
definition
Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.