loading...| Preferred Name |
Simeprevir |
|
| Synonyms |
TMC-435350 |
|
| Definitions |
Oral HCV-PROTEASE INHIBITOR effective against hepatitis C virus (HCV) serine protease NS3/4A. It is used in the treatment of chronic hepatitis C (Antivirals) genotype 1 infection in adults with compensated liver disease, including CIRRHOSIS. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D000069616 |
|
| altLabel |
TMC-435350 TMC435350 TMC 435350 N-(17-(2-(4-isopropylthiazole-2-yl)-7-methoxy-8-methylquinolin-4-yloxy)-13-methyl-2,14-dioxo-3,13-diazatricyclo(13.3.0.04,6)octadec-7-ene-4-carbonyl)(cyclopropyl)sulfonamide TMC435 TMC 435 435350, TMC Olysio 435, TMC TMC-435 |
|
| AQL |
AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR |
|
| cui |
C2745868 C2605855 C2605856 C3696409 |
|
| DC |
1 |
|
| definition |
Oral HCV-PROTEASE INHIBITOR effective against hepatitis C virus (HCV) serine protease NS3/4A. It is used in the treatment of chronic hepatitis C (Antivirals) genotype 1 infection in adults with compensated liver disease, including CIRRHOSIS. |
|
| DX |
20160101 |
|
| HN |
2016 (2008) |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
9WS5RD66HZ 0 |
|
| isa | ||
| LT |
TRD |
|
| Machine permutation |
2016; SIMEPREVIR was indexed under SULFONAMIDES and HETEROCYCLIC COMPOUNDS, 3-RING 2008-2015 |
|
| MDA |
20150710 |
|
| MMR |
20160531 |
|
| MN |
D03.633.300.819 D02.886.590.700.700 |
|
| notation |
D000069616 |
|
| PA |
D000998 D011480 |
|
| prefLabel |
Simeprevir |
|
| TERMUI |
T763452 T729073 T763453 T729070 T000880817 T851452 T763454 T729072 T729071 |
|
| TH |
NLM (2016) NLM (2008) NLM (2010) NLM (2014) |
|
| tui |
T109 T121 |
|
| subClassOf |