loading...| Preferred Name |
chlorozotocin |
|
| Synonyms |
2-((((2-chloroethyl)nitrosoamino)-carbonyl)amino)-2-deoxy-D-glucose |
|
| ID |
http://purl.bioontology.org/ontology/MESH/C007028 |
|
| altLabel |
2-((((2-chloroethyl)nitrosoamino)-carbonyl)amino)-2-deoxy-D-glucose 2-(3-(2-chloroethyl)-3-nitrodoureido)-2-deoxy-D-glucopyranose NSC-178248 NSC 178,248 chlorozotocin, (L)-isomer |
|
| cui |
C0133016 C0951593 C0055465 |
|
| Has mapping qualifier | ||
| HM |
D013311/Q000031 |
|
| Inverse of RB |
3053LTY75Z 69839-80-1 0 |
|
| isa | ||
| Mapped to | ||
| MDA |
19750101 |
|
| MeSH Frequency |
133 |
|
| MMR |
20150818 |
|
| notation |
C007028 |
|
| PA |
D002273 D000970 |
|
| PI |
ETHYL CHLORIDE (75-78) |
|
| prefLabel |
chlorozotocin |
|
| RR |
54749-90-5 (chlorozotocin) 69839-80-1 ((L)-isomer) |
|
| SC |
1 |
|
| Scope Statement |
2-chloroethyl analog of streptozotocin with superior activity against leukemia L1210 and reduced bone marrow toxicity; RN given refers to (D)-isomer; structure |
|
| SRC |
Cancer Treat Rep 62(1):31;1978 Cancer 43(6):2189;1979 Cancer Chemother Pharmacol 1979;3(4):217 Cancer Treat Rep 60(6):699;1976 Cancer Treat Rep 63(1):17;1979 Cancer 40(5) suppl:2640;1977 Biochem Pharmacol 26:2331;1977 Toxicology 12(1):3l;1979 Cancer Res 37(8):2615;1977 Cancer Treat Rep 60(6):801;1976 NE J Med 301(12):662;1979 Cancer Res 37(3):783;1977 Cancer Res 1980;40(1):50 Cancer Treat Rep 62(8):1145;1978 Cancer Treat Rep 1979;63(8):1409 Dokl Akad Nauk SSSR 245(1):260;1979 Oncology 1980;37(3):177 Cancer Chemother Pharmacol 1(1):15;1978 J Med Assoc Ga 66(9):729;1977 J Clin Invest 1979;64(4):1103 Clin Pharmacol Ther 23(6):712;1978 J Med Chem 22(5):597;1979 J Med Chem 18(1):104;1975 |
|
| TERMUI |
T079949 T544202 T339801 T079948 T079950 |
|
| TH |
NLM (1975) INN (19XX) NLM (2003) FDA SRS (2015) |
|
| tui |
T109 T195 |