Preferred Name

alveolar macrophage

Synonyms
ID

http://purl.obolibrary.org/obo/LMMA_00226

contained_within

http://purl.obolibrary.org/obo/LMMA_00068

http://purl.obolibrary.org/obo/LMMA_00063

http://purl.obolibrary.org/obo/LMMA_00818

definition

A tissue-resident macrophage found in the alveoli (lumen) of the lungs that is repsonsible for the clearance of inhaled particles, microorganisms, and pulmonary surfactant. Ingestion of small inhaled particles results in degradation and presentation of the antigen to immunocompetent cells. These cells are long-lived and self renewing. Marker profile: CD45 pos, CD68 high, F4/80 high, CD11b neg, CD11c high,MCHCII low, CD103 neg (1), CD64 pos and SiglecF high (2).

Developmental_Stage

http://purl.obolibrary.org/obo/LMMA_00509

display

true

evidence

published

has_domain

http://www.lungmap.net/ontologies/database#cell

hasDbXref

CL:0000583

LMHA:00226

id

LMMA:00226

in_organism

http://www.lungmap.net/ontologies/data#taxid_10090

in_stage

http://purl.obolibrary.org/obo/LMMA_00266

http://purl.obolibrary.org/obo/LMMA_00268

in_stage_range

http://purl.obolibrary.org/obo/LMMA_00670

http://purl.obolibrary.org/obo/LMMA_00669

label

alveolar macrophage

notation

LMMA:00226

prefLabel

alveolar macrophage

Theiler_Stage

http://purl.obolibrary.org/obo/LMMA_00375

http://purl.obolibrary.org/obo/LMMA_00376

subClassOf

http://purl.obolibrary.org/obo/LMMA_00182

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