loading...| Preferred Name |
abacavir |
|
| Synonyms |
{(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol |
|
| Definitions |
A 2,6-diaminopurine that is (1S)-cyclopent-2-en-1-ylmethanol in which the pro-R hydrogen at the 4-position is substituted by a 2-amino-6-(cyclopropylamino)-9H-purin-9-yl group. A nucleoside analogue reverse transcriptase inhibitor (NRTI) with antiretroviral activity against HIV, it is used (particularly as the sulfate) with other antiretrovirals in combination therapy of HIV infection. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_421707 |
|
| database cross reference |
PMID:11806176 PMID:15887959 PMID:18029175 PMID:11678376 PMID:16458506 PMID:25017682 Drug_Central:34 PMID:16759112 PMID:12781181 PMID:26024233 PMID:17172311 PMID:25674793 PMID:24751900 PMID:17870541 PMID:16539393 PMID:18549801 Reaxys:7493116 Beilstein:7493116 CAS:136470-78-5 DrugBank:DB01048 |
|
| definition |
A 2,6-diaminopurine that is (1S)-cyclopent-2-en-1-ylmethanol in which the pro-R hydrogen at the 4-position is substituted by a 2-amino-6-(cyclopropylamino)-9H-purin-9-yl group. A nucleoside analogue reverse transcriptase inhibitor (NRTI) with antiretroviral activity against HIV, it is used (particularly as the sulfate) with other antiretrovirals in combination therapy of HIV infection. |
|
| has role |
http://purl.obolibrary.org/obo/CHEBI_53756 |
|
| has_exact_synonym |
{(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol Abacavir |
|
| has_related_synonym |
abacavir ABC {(1S-cis)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol |
|
| label |
abacavir |
|
| prefixIRI |
CHEBI:421707 |
|
| prefLabel |
abacavir |
|
| subClassOf |