loading...| Preferred Name |
PI3K/AKT Signaling in Cancer |
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| Definitions |
Reviewed: Yuzugullu, Haluk, 2012-08-13 This pathway describes how normal signaling by PI3K/AKT, presented in the contained module 'PIP3 Activates AKT Signaling' and recently reviewed by Manning and Cantley in 2007, is perturbed in cancer, as described in the contained module 'Constitutive Signaling by PI3K/AKT'. Please refer to Liu et al. 2009 and Hollander et al. 2011 for recent reviews. Edited: Matthews, L, 2012-08-03 Authored: Orlic-Milacic, M, 2012-07-18 Reviewed: Zhao, Jean J, 2012-08-13 Reviewed: Thorpe, Lauren, 2012-08-13 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0016282 |
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| comment |
Reviewed: Yuzugullu, Haluk, 2012-08-13 This pathway describes how normal signaling by PI3K/AKT, presented in the contained module 'PIP3 Activates AKT Signaling' and recently reviewed by Manning and Cantley in 2007, is perturbed in cancer, as described in the contained module 'Constitutive Signaling by PI3K/AKT'. Please refer to Liu et al. 2009 and Hollander et al. 2011 for recent reviews. Edited: Matthews, L, 2012-08-03 Authored: Orlic-Milacic, M, 2012-07-18 Reviewed: Zhao, Jean J, 2012-08-13 Reviewed: Thorpe, Lauren, 2012-08-13 |
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| definition source |
Pubmed17604717 Pubmed19644473 Reactome, http://www.reactome.org Pubmed21430697 |
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| label |
PI3K/AKT Signaling in Cancer |
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| prefixIRI |
HINO:0016282 |
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| prefLabel |
PI3K/AKT Signaling in Cancer |
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| seeAlso |
Reactome Database ID Release 432219528 ReactomeREACT_147723 |
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