Preferred Name |
Proteolysis of the IGF:IGFBP-3:ALS Complex by Prostate-specific Antigen |
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Synonyms |
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Definitions |
Reviewed: D'Eustachio, P, Matthews, L, Gillespie, ME, 2008-12-02 16:25:31 Edited: May, B, Gopinathrao, G, 2008-11-19 20:02:07 Prostate specific Antigen (PSA) cleaves IGFBP-3 in the IGF:IGFBP-3:ALS Complex between amino acids 186 and 187. Other cleavage sites were observed but not reproducibly. These may have been caused by impurities in the PSA preparation. |
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ID |
http://purl.obolibrary.org/obo/HINO_0008765 |
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comment |
Reviewed: D'Eustachio, P, Matthews, L, Gillespie, ME, 2008-12-02 16:25:31 Edited: May, B, Gopinathrao, G, 2008-11-19 20:02:07 Prostate specific Antigen (PSA) cleaves IGFBP-3 in the IGF:IGFBP-3:ALS Complex between amino acids 186 and 187. Other cleavage sites were observed but not reproducibly. These may have been caused by impurities in the PSA preparation. |
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definition source |
Pubmed7525824 Pubmed11751371 Pubmed7525634 Pubmed1383255 Pubmed12379487 Reactome, http://www.reactome.org Pubmed12466191 Pubmed8817670 Pubmed7538844 Pubmed10218588 Pubmed17047378 |
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has input | ||
has output |
http://purl.obolibrary.org/obo/UniProt_P17936 |
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label |
Proteolysis of the IGF:IGFBP-3:ALS Complex by Prostate-specific Antigen |
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prefixIRI |
HINO:0008765 |
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prefLabel |
Proteolysis of the IGF:IGFBP-3:ALS Complex by Prostate-specific Antigen |
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seeAlso |
ReactomeREACT_15465 EC Number: 3.4.21 Reactome Database ID Release 43381466 |
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subClassOf |