Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Proteolysis of the IGF:IGFBP-3:ALS Complex by Thrombin

Synonyms
Definitions

Reviewed: D'Eustachio, P, Matthews, L, Gillespie, ME, 2008-12-02 16:25:31 Edited: May, B, Gopinathrao, G, 2008-11-19 20:02:07 Thrombin cleaves IGFBP-3 in the IGF:IGFBP-3:ALS Complex between amino acids 124 and 125 and between amino acids 233 and 234, releasing IGF.

ID

http://purl.obolibrary.org/obo/HINO_0008764

comment

Reviewed: D'Eustachio, P, Matthews, L, Gillespie, ME, 2008-12-02 16:25:31

Edited: May, B, Gopinathrao, G, 2008-11-19 20:02:07

Thrombin cleaves IGFBP-3 in the IGF:IGFBP-3:ALS Complex between amino acids 124 and 125 and between amino acids 233 and 234, releasing IGF.

definition source

Pubmed12379487

Reactome, http://www.reactome.org

Pubmed12466191

Pubmed11739083

Pubmed8817670

Pubmed17047378

has input

http://purl.obolibrary.org/obo/HINO_0017493

has output

http://purl.obolibrary.org/obo/UniProt_P17936

http://purl.obolibrary.org/obo/UniProt_P35858

http://purl.obolibrary.org/obo/HINO_0026720

label

Proteolysis of the IGF:IGFBP-3:ALS Complex by Thrombin

prefixIRI

HINO:0008764

prefLabel

Proteolysis of the IGF:IGFBP-3:ALS Complex by Thrombin

seeAlso

Reactome Database ID Release 43381446

EC Number: 3.4.21

ReactomeREACT_15373

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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