loading...| Preferred Name |
meningococcal meningitis |
|
| Synonyms |
Meningitis, Meningococcal meningococcal meningitis |
|
| Definitions |
A fulminant infection of the meninges and subarachnoid fluid by the bacterium NEISSERIA MENINGITIDIS, producing diffuse inflammation and peri-meningeal venous thromboses. Clinical manifestations include FEVER, nuchal rigidity, SEIZURES, severe HEADACHE, petechial rash, stupor, focal neurologic deficits, HYDROCEPHALUS, and COMA. The organism is usually transmitted via nasopharyngeal secretions and is a leading cause of meningitis in children and young adults. Organisms from Neisseria meningitidis serogroups A, B, C, Y, and W-135 have been reported to cause meningitis. (From Adams et al., Principles of Neurology, 6th ed, pp689-701; Curr Opin Pediatr 1998 Feb;10(1):13-8) An acute bacterial disease caused by Neisseria meningitides that presents usually, but not always, with a rash (non blanching petechial or purpuric rash), progressively developing signs of meningitis (fever, vomiting, headache, photophobia, and neck stiffness) and later leading to confusion, delirium and drowsiness. Neck stiffness and photophobia are often absent in infants and young children who may manifest nonspecific signs such as irritability, inconsolable crying, poor feeding, and a bulging fontanel. Meningococcal meningitis may also present as part of early or late onset sepsis in neonates. The disease is potentially fatal. Surviving patients may develop neurological sequelae that include sensorineural hearing loss, seizures, spasticity, attention deficits and intellectual disability. |
|
| ID |
http://www.ebi.ac.uk/efo/EFO_1001040 |
|
| closeMatch | ||
| database_cross_reference |
ICD10:A39.0 SNOMEDCT:192644005 MedDRA:10027276 MeSH:D008585 DOID:9929 ICD9:036.0 DOID:0080176 MedDRA:10027249 ICD10EXP:A39.0+ ICD10EXP:G01* Orphanet:33475 SCTID:192644005 ICD10CM:A39.0 NORD:1438 GARD:18809 MESH:D008585 UMLS:C0025294 MONDO:0018059 |
|
| definition |
A fulminant infection of the meninges and subarachnoid fluid by the bacterium NEISSERIA MENINGITIDIS, producing diffuse inflammation and peri-meningeal venous thromboses. Clinical manifestations include FEVER, nuchal rigidity, SEIZURES, severe HEADACHE, petechial rash, stupor, focal neurologic deficits, HYDROCEPHALUS, and COMA. The organism is usually transmitted via nasopharyngeal secretions and is a leading cause of meningitis in children and young adults. Organisms from Neisseria meningitidis serogroups A, B, C, Y, and W-135 have been reported to cause meningitis. (From Adams et al., Principles of Neurology, 6th ed, pp689-701; Curr Opin Pediatr 1998 Feb;10(1):13-8) An acute bacterial disease caused by Neisseria meningitides that presents usually, but not always, with a rash (non blanching petechial or purpuric rash), progressively developing signs of meningitis (fever, vomiting, headache, photophobia, and neck stiffness) and later leading to confusion, delirium and drowsiness. Neck stiffness and photophobia are often absent in infants and young children who may manifest nonspecific signs such as irritability, inconsolable crying, poor feeding, and a bulging fontanel. Meningococcal meningitis may also present as part of early or late onset sepsis in neonates. The disease is potentially fatal. Surviving patients may develop neurological sequelae that include sensorineural hearing loss, seizures, spasticity, attention deficits and intellectual disability. |
|
| exactMatch |
http://purl.bioontology.org/ontology/ICD10CM/A39.0 http://identifiers.org/mesh/D008585 http://linkedlifedata.com/resource/umls/id/C0025294 http://purl.obolibrary.org/obo/DOID_0080176 |
|
| has_exact_synonym |
Meningitis, Meningococcal meningococcal meningitis |
|
| id |
EFO:1001040 |
|
| in_subset |
http://purl.obolibrary.org/obo/mondo#ordo_disease http://purl.obolibrary.org/obo/mondo#rare http://purl.obolibrary.org/obo/mondo#nord_rare |
|
| label |
meningococcal meningitis |
|
| notation |
EFO:1001040 |
|
| prefLabel |
meningococcal meningitis |
|
| term editor |
Sirarat Sarntivijai |
|
| subClassOf |