Preferred Name |
gastroesophageal reflux disease |
|
Synonyms |
Gastro-Esophageal Reflux Reflux, Gastro-oesophageal Gastro-oesophageal Reflux Gastro oesophageal Reflux GASTROESOPHAGEAL REFLUX DIS Reflux, Gastroesophageal Gastroesophageal Reflux Reflux, Gastro-Esophageal Esophageal Reflux Gastro Esophageal Reflux GERD reflux gastro-esophageal reflux Gastresophageal reflux gastroesophageal reflux GERD - gastro-esophageal reflux disease gastroesophageal reflux disease acid reflux gastroesophageal reflux, pediatric gastroesophageal reflux, paediatric ger |
|
Definitions |
Retrograde flow of gastric juice (GASTRIC ACID) and/or duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the distal ESOPHAGUS, commonly due to incompetence of the LOWER ESOPHAGEAL SPHINCTER. A chronic disorder characterized by reflux of the gastric and/or duodenal contents into the distal esophagus. It is usually caused by incompetence of the lower esophageal sphincter. Symptoms include heartburn and acid indigestion. It may cause injury to the esophageal mucosa. |
|
ID |
http://www.ebi.ac.uk/efo/EFO_0003948 |
|
database_cross_reference |
MeSH:D005764 NCIt:C26781 MedDRA:10038262 MedDRA:10066874 SNOMEDCT:235595009 ICD9:530.81 OMIM:109350 DOID:8534 HP:0002020 ICD10:K21 SCTID:235595009 MONDO:0007186 NCIT:C26781 UMLS:C0017168 MESH:D005764 |
|
definition |
Retrograde flow of gastric juice (GASTRIC ACID) and/or duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the distal ESOPHAGUS, commonly due to incompetence of the LOWER ESOPHAGEAL SPHINCTER. A chronic disorder characterized by reflux of the gastric and/or duodenal contents into the distal esophagus. It is usually caused by incompetence of the lower esophageal sphincter. Symptoms include heartburn and acid indigestion. It may cause injury to the esophageal mucosa. |
|
exactMatch |
http://identifiers.org/snomedct/235595009 http://identifiers.org/mesh/D005764 http://purl.obolibrary.org/obo/NCIT_C26781 |
|
gwas_trait |
true |
|
has_exact_synonym |
Gastro-Esophageal Reflux Reflux, Gastro-oesophageal Gastro-oesophageal Reflux Gastro oesophageal Reflux GASTROESOPHAGEAL REFLUX DIS Reflux, Gastroesophageal Gastroesophageal Reflux Reflux, Gastro-Esophageal Esophageal Reflux Gastro Esophageal Reflux GERD reflux gastro-esophageal reflux Gastresophageal reflux gastroesophageal reflux GERD - gastro-esophageal reflux disease gastroesophageal reflux disease acid reflux |
|
has_related_synonym |
gastroesophageal reflux, pediatric gastroesophageal reflux, paediatric ger |
|
id |
EFO:0003948 |
|
in_subset | ||
label |
gastroesophageal reflux disease |
|
notation |
EFO:0003948 |
|
prefLabel |
gastroesophageal reflux disease |
|
term editor |
Tomasz Adamusiak |
|
subClassOf |
http://www.ebi.ac.uk/efo/EFO_0000508 |