loading...| Preferred Name |
thrombopoietin |
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| Synonyms |
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| Definitions |
Thrombopoietin (THPO) also known as megakaryocyte growth and development factor (MGDF) is a protein that in humans is encoded by the THPO gene. Thrombopoietin is a glycoprotein hormone produced mainly by the liver and the kidney that regulates the production of platelets by the bone marrow. It stimulates the production and differentiation of megakaryocytes, the bone marrow cells that fragment into large numbers of platelets.[1] |
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| ID |
http://www.ebi.ac.uk/efo/EFO_0003236 |
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| database_cross_reference |
OMIM:600044 CASRN:9014-42-0 SNOMEDCT:18617001 MeSH:D013926 DSSTox_Generic_SID:40918 NCIt:C20441 |
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| definition |
Thrombopoietin (THPO) also known as megakaryocyte growth and development factor (MGDF) is a protein that in humans is encoded by the THPO gene. Thrombopoietin is a glycoprotein hormone produced mainly by the liver and the kidney that regulates the production of platelets by the bone marrow. It stimulates the production and differentiation of megakaryocytes, the bone marrow cells that fragment into large numbers of platelets.[1] |
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| definition_citation | ||
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| label |
thrombopoietin |
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| prefixIRI |
efo1:EFO_0003236 |
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| prefLabel |
thrombopoietin |
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| term editor |
Tomasz Adamusiak Ele Holloway James Malone |
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| subClassOf |