loading...| Preferred Name |
artemether |
|
| Synonyms |
(3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-methoxy-3,6,9-trimethyldecahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepine (1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecane 10-methoxy-1,5,9-trimethyl-(1R,4S,5R,8S,9R,10S,12R,13R)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane dihydroartemisinin methyl ether beta-dihydroartemisinin methyl ether artemisininelactol methyl ether artemetherum beta-artemether methyl-dihydroartemisinine artemetero artemether |
|
| Definitions |
An artemisinin derivative that is artemisinin in which the lactone has been converted to the corresponding lactol methyl ether. It is used in combination with lumefantrine as an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_195280 |
|
| charge |
0 |
|
| database_cross_reference |
PMID:17404003 CAS:71963-77-4 PMID:12781185 PMID:3279208 Drug_Central:245 KEGG:D02483 PMID:18243702 Beilstein:6569878 PMID:11141088 PMID:16033274 Wikipedia:Artemether DrugBank:DB06697 PMID:17242150 LINCS:LSM-5519 |
|
| definition |
An artemisinin derivative that is artemisinin in which the lactone has been converted to the corresponding lactol methyl ether. It is used in combination with lumefantrine as an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria. |
|
| formula |
C16H26O5 |
|
| has role | ||
| has_exact_synonym |
(3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-methoxy-3,6,9-trimethyldecahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepine |
|
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
(1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecane 10-methoxy-1,5,9-trimethyl-(1R,4S,5R,8S,9R,10S,12R,13R)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane dihydroartemisinin methyl ether beta-dihydroartemisinin methyl ether artemisininelactol methyl ether artemetherum beta-artemether methyl-dihydroartemisinine artemetero artemether |
|
| has_RxCUI |
18343 |
|
| id |
CHEBI:195280 |
|
| in_subset | ||
| inchi |
InChI=1S/C16H26O5/c1-9-5-6-12-10(2)13(17-4)18-14-16(12)11(9)7-8-15(3,19-14)20-21-16/h9-14H,5-8H2,1-4H3/t9-,10-,11+,12+,13+,14-,15-,16-/m1/s1 |
|
| inchikey |
SXYIRMFQILZOAM-HVNFFKDJSA-N |
|
| label |
artemether |
|
| mass |
298.37460 |
|
| monoisotopicmass |
298.17802 |
|
| notation |
CHEBI:195280 |
|
| prefLabel |
artemether |
|
| smiles |
[H][C@@]12CC[C@@]3(C)OO[C@@]11[C@@]([H])(CC[C@H]2C)[C@@H](C)[C@@H](OC)O[C@]1([H])O3 |
|
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_59770 http://purl.obolibrary.org/obo/CHEBI_72588 |