The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

papaverine

Synonyms

1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxyisoquinoline

C20H21NO4

ID

http://purl.obolibrary.org/obo/dinto_DB01113

AHFScode

24:12.92

ATCCode

G04BE02

A03AD01

CASRN

61-25-6

DBBrand

dilaves

pavatym

alapav

cepaverin

pavatest

cardoverina

drapavel

paverolan

robaxapap

forpavin

dispamil

cerebid

vasal

optenyl

pavacap

pavacels

delapav

papacon

pavakey

spasmo-nit

therapav

papanerin

panergon

cerespan

papital t.r.

pavacen

papaversan

pavadel

qua bid

paveron

vaso-pav

paptial t.r.

pavased

papalease

pamelon

pavagen

pavabid

artegodan

pavarine

pavabid hp

papanerine

genabid

pavatine

pavacot

pameion

papanerin-hcl

ro-papav

pap h

pavnell

myobid

durapav

dynovas

cardiospan

DBSynonym

papaverinium chloride

chlorhydrate de papaverine

papaverin

papaverine hydrochloride

papaverine hcl

papaverine chlorohydrate

papavarine chlorhydrate

papaverine monohydrochloride

Definition

An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels. [PubChem]

has effect

http://purl.obolibrary.org/obo/OAE_0000081

http://purl.obolibrary.org/obo/OAE_0000355

http://purl.obolibrary.org/obo/OAE_0000390

http://purl.obolibrary.org/obo/OAE_0000401

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0001024

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000242

http://purl.obolibrary.org/obo/OAE_0000396

http://purl.obolibrary.org/obo/OAE_0000460

http://purl.obolibrary.org/obo/OAE_0000021

http://purl.obolibrary.org/obo/OAE_0000602

http://purl.obolibrary.org/obo/OAE_0000210

http://purl.obolibrary.org/obo/OAE_0000362

has pharmacological target

http://purl.obolibrary.org/obo/dinto_0074

InChI

InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3

InChIKey

InChIKey=XQYZDYMELSJDRZ-UHFFFAOYSA-N

inhibits

http://purl.obolibrary.org/obo/dinto_3961

http://purl.obolibrary.org/obo/dinto_0074

label

papaverine

may interact with

http://purl.obolibrary.org/obo/dinto_DB06274

http://purl.obolibrary.org/obo/CHEBI_50861

prefixIRI

obo2:dinto_DB01113

prefLabel

papaverine

SMILES

COC1=C(OC)C=C(CC2=NC=CC3=CC(OC)=C(OC)C=C23)C=C1

Synonym

1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxyisoquinoline

C20H21NO4

xref

PubChem Compound:4680

BindingDB:14754

ChemSpider:4518

PharmGKB:PA164745550

Drugs.com:http://www.drugs.com/cdi/papaverine.html

Drugs Product Database (DPD):9881

RxList:http://www.rxlist.com/cgi/generic/papaverine.htm

Wikipedia:http://en.wikipedia.org/wiki/Papaverine

PDB:EV1

PubChem Substance:46508003

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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http://purl.bioontology.org/ontology/LNC/MTHU003466 LOINC LOOM
http://www.drugbank.ca/drugs/DB01113 FTC LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C726 NCIT LOOM
http://www.co-ode.org/ontologies/galen#Papaverine GALEN LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Papaverine APAONTO LOOM
https://bioportal.bioontology.org/ontologies/FTDM.owl#papaverine FASTO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.132.577.750 RH-MESH LOOM
http://purl.bioontology.org/ontology/UATC/A03AD01 ATC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.132.098.666 RH-MESH LOOM
http://purl.bioontology.org/ontology/UATC/G04BE02 ATC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372784001 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/LNC/LP18145-0 LOINC LOOM
http://purl.bioontology.org/ontology/VANDF/4019875 VANDF LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147960 OCVDAE LOOM
http://stirdf.jst.go.jp/id/200907038181637649 IOBC LOOM
http://purl.bioontology.org/ontology/MESH/D010208 MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/7895 RXNORM LOOM
http://purl.bioontology.org/ontology/CSP/2530-5634 CRISP LOOM
http://purl.bioontology.org/ontology/SNMI/C-815D0 SNMI LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D010208 RH-MESH LOOM
http://purl.jp/bio/4/id/200906024866360289 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.531.085.666 RH-MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_28241 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_28241 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_28241 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_28241 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_28241 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_28241 NIFSTD LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147960 NDFRT LOOM
http://purl.bioontology.org/ontology/RCD/gh3.. RCD LOOM