loading...| Preferred Name |
papaverine |
|
| Synonyms |
C20H21NO4 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxyisoquinoline |
|
| ID |
http://purl.obolibrary.org/obo/dinto_DB01113 |
|
| AHFScode |
24:12.92 |
|
| ATCCode |
A03AD01 G04BE02 |
|
| CASRN |
61-25-6 |
|
| DBBrand |
paptial t.r. pavarine ro-papav papanerine artegodan vasal forpavin dispamil robaxapap papanerin pavased qua bid pavabid cerespan papacon cardoverina dynovas pavacels genabid pavabid hp cardiospan pavnell optenyl pamelon spasmo-nit paverolan panergon pavatest delapav dilaves pavacen cepaverin drapavel durapav pavadel pavatine pameion myobid pavacap alapav vaso-pav cerebid therapav pavagen pavatym papaversan pap h papalease papital t.r. paveron pavacot papanerin-hcl pavakey |
|
| DBSynonym |
papaverin papaverinium chloride papaverine monohydrochloride chlorhydrate de papaverine papaverine hcl papaverine hydrochloride papaverine chlorohydrate papavarine chlorhydrate |
|
| Definition |
An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels. [PubChem] |
|
| has effect |
http://purl.obolibrary.org/obo/OAE_0000081 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000210 http://purl.obolibrary.org/obo/OAE_0000021 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0001024 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000390 |
|
| has pharmacological target | ||
| InChI |
InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3 |
|
| InChIKey |
InChIKey=XQYZDYMELSJDRZ-UHFFFAOYSA-N |
|
| inhibits | ||
| label |
papaverine |
|
| may interact with | ||
| prefixIRI |
obo2:dinto_DB01113 |
|
| prefLabel |
papaverine |
|
| SMILES |
COC1=C(OC)C=C(CC2=NC=CC3=CC(OC)=C(OC)C=C23)C=C1 |
|
| Synonym |
C20H21NO4 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxyisoquinoline |
|
| xref |
RxList:http://www.rxlist.com/cgi/generic/papaverine.htm PubChem Compound:4680 BindingDB:14754 ChemSpider:4518 Drugs.com:http://www.drugs.com/cdi/papaverine.html Wikipedia:http://en.wikipedia.org/wiki/Papaverine PubChem Substance:46508003 PDB:EV1 Drugs Product Database (DPD):9881 PharmGKB:PA164745550 |
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| subClassOf |