The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

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Preferred Name	glipizide
Synonyms	C21H27N5O4S N-[2-(4-{[(cyclohexylcarbamoyl)amino]sulfonyl}phenyl)ethyl]-5-methylpyrazine-2-carboxamide
ID	http://purl.obolibrary.org/obo/dinto_DB01067
activates	http://purl.obolibrary.org/obo/dinto_2153
ATCCode	A10BB07
CASRN	29094-61-9
DBBrand	glupitel melizide glyde digrin dipazide minidab napizide glupizide minodiab minidiab glipizide extended-release tablets glidiab metaglip glucotrol xl mindiab glipid glucotrol aldiab glide glibenese glibetin glican glucolip ozidia sucrazide gluco-rite glucozide
DBSynonym	glydiazinamide glipizidum [inn-latin] glipizida [inn-spanish]
Definition	An oral hypoglycemic agent which is rapidly absorbed and completely metabolized. [PubChem]
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0000905 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000902 http://purl.obolibrary.org/obo/OAE_0000391 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000479 http://purl.obolibrary.org/obo/OAE_0000561 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0000611 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000021 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000317 http://purl.obolibrary.org/obo/OAE_0000660 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0000287 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000375 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0001275 http://purl.obolibrary.org/obo/OAE_0000517 http://purl.obolibrary.org/obo/OAE_0001057 http://purl.obolibrary.org/obo/OAE_0001295 http://purl.obolibrary.org/obo/OAE_0001374 http://purl.obolibrary.org/obo/OAE_0000268 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0001106 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000343 http://purl.obolibrary.org/obo/OAE_0000536 http://purl.obolibrary.org/obo/OAE_0000385 http://purl.obolibrary.org/obo/OAE_0000468 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0000394 http://purl.obolibrary.org/obo/OAE_0000402 http://purl.obolibrary.org/obo/OAE_0000350
has pharmacological target	http://purl.obolibrary.org/obo/dinto_2142
InChI	InChI=1S/C21H27N5O4S/c1-15-13-24-19(14-23-15)20(27)22-12-11-16-7-9-18(10-8-16)31(29,30)26-21(28)25-17-5-3-2-4-6-17/h7-10,13-14,17H,2-6,11-12H2,1H3,(H,22,27)(H2,25,26,28)
InChIKey	InChIKey=ZJJXGWJIGJFDTL-UHFFFAOYSA-N
inhibits	http://purl.obolibrary.org/obo/dinto_2142
is metabolised by	http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_0901
label	glipizide
may interact with	http://purl.obolibrary.org/obo/CHEBI_8214 http://purl.obolibrary.org/obo/CHEBI_8499 http://purl.obolibrary.org/obo/CHEBI_4856 http://purl.obolibrary.org/obo/CHEBI_4031 http://purl.obolibrary.org/obo/CHEBI_15365 http://purl.obolibrary.org/obo/CHEBI_3750 http://purl.obolibrary.org/obo/CHEBI_3127 http://purl.obolibrary.org/obo/dinto_DB00373 http://purl.obolibrary.org/obo/CHEBI_17698 http://purl.obolibrary.org/obo/CHEBI_3441 http://purl.obolibrary.org/obo/CHEBI_2904 http://purl.obolibrary.org/obo/CHEBI_6904 http://purl.obolibrary.org/obo/CHEBI_48574 http://purl.obolibrary.org/obo/dinto_DB00052 http://purl.obolibrary.org/obo/CHEBI_2379 http://purl.obolibrary.org/obo/dinto_DB01580 http://purl.obolibrary.org/obo/CHEBI_7444 http://purl.obolibrary.org/obo/CHEBI_6343 http://purl.obolibrary.org/obo/CHEBI_27999 http://purl.obolibrary.org/obo/CHEBI_28077
prefixIRI	obo2:dinto_DB01067
prefLabel	glipizide
SMILES	CC1=CN=C(C=N1)C(=O)NCCC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC1CCCCC1
Synonym	C21H27N5O4S N-[2-(4-{[(cyclohexylcarbamoyl)amino]sulfonyl}phenyl)ethyl]-5-methylpyrazine-2-carboxamide
xref	Drugs.com:http://www.drugs.com/glipizide.html PharmGKB:PA449762 PubChem Substance:46505865 National Drug Code Directory:0378-1105-01 ChemSpider:3359 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/cx1655.shtml PubChem Compound:3478 Wikipedia:http://en.wikipedia.org/wiki/Glipizide RxList:http://www.rxlist.com/cgi/generic/glip.htm BindingDB:50012956
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_5384	CHEBI	LOOM
http://purl.obolibrary.org/obo/MESH_D005913	BERO	LOOM
http://purl.jp/bio/4/id/200906081603348440	IOBC	LOOM
https://go.drugbank.com/drugs/DB01067	MDM	LOOM
http://purl.bioontology.org/ontology/NDDF/000913	NDDF	LOOM
http://www.drugbank.ca/drugs/DB01067	FTC	LOOM
http://purl.obolibrary.org/obo/NCIT_C29074	BERO	LOOM
http://mimi.case.edu/ontologies/2009/9/DrugOntology#glipizide	SDO	LOOM
http://purl.bioontology.org/ontology/CSP/4001-0060	CRISP	LOOM
http://purl.bioontology.org/ontology/SNMI/C-A2430	SNMI	LOOM
http://purl.bioontology.org/ontology/VANDF/4018508	VANDF	LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000775361	PDQ	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0017642	OCHV	LOOM
http://purl.obolibrary.org/obo/OMIT_0007106	OMIT	LOOM
http://purl.bioontology.org/ontology/RXNORM/4821	RXNORM	LOOM
http://stirdf.jst.go.jp/id/200907020740128770	IOBC	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU062931	LOINC	LOOM
http://purl.bioontology.org/ontology/ATC/A10BB07	ATC	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.590.795.500	RH-MESH	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29074	NCIT	LOOM
http://www.co-ode.org/ontologies/galen#Glipizide	GALEN	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146830	NDFRT	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387143009	SNOMEDCT	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D005913	RH-MESH	LOOM
http://purl.bioontology.org/ontology/LNC/LP14719-6	LOINC	LOOM
http://purl.obolibrary.org/obo/CHEBI_5384	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_5384	FIDEO	LOOM
http://purl.obolibrary.org/obo/CHEBI_5384	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_5384	DRON	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#5526	OCHV	LOOM
http://purl.bioontology.org/ontology/MESH/D005913	MESH	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017439	PMAPP-PMO	LOOM