tioconazole

1-{2-[(2-chlorothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole

C16H13Cl3N2OS

http://purl.obolibrary.org/obo/dinto_DB01007

D01AC07

G01AF08

http://purl.obolibrary.org/obo/dinto_2157

65899-73-2

tz-3

trosyl

zoniden

trosyd af

trosyd j

fungibacid

monistat 1

vagistat-1

gynecure

gyno-trosyd

trosyd

vagistat

tioconazolum [inn-latin]

tioconazol [inn-spanish]

Tioconazole is an antifungal medication of the Imidazole class used to treat infections caused by a fungus or yeast. Tioconazole topical (skin) preparations are also available for ringworm, jock itch, athlete s foot, and tinea versicolor or "sun fungus". Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. In this way, tioconazole inhibits ergosterol synthesis, resulting in increased cellular permeability.

http://purl.obolibrary.org/obo/dinto_2157

InChI=1S/C16H13Cl3N2OS/c17-12-1-2-13(14(18)7-12)15(8-21-5-4-20-10-21)22-9-11-3-6-23-16(11)19/h1-7,10,15H,8-9H2

InChIKey=QXHHHPZILQDDPS-UHFFFAOYSA-N

http://purl.obolibrary.org/obo/dinto_4171

http://purl.obolibrary.org/obo/dinto_3102

http://purl.obolibrary.org/obo/dinto_2651

http://purl.obolibrary.org/obo/dinto_2058

http://purl.obolibrary.org/obo/dinto_0293

http://purl.obolibrary.org/obo/dinto_0291

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_1221

tioconazole

obo2:dinto_DB01007

tioconazole

ClC1=C(COC(CN2C=CN=C2)C2=C(Cl)C=C(Cl)C=C2)C=CS1

1-{2-[(2-chlorothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole

C16H13Cl3N2OS

ChemSpider:5282

PubChem Substance:46508604

PharmGKB:PA164746156

National Drug Code Directory:24385-374-82

PubChem Compound:5482

Wikipedia:http://en.wikipedia.org/wiki/Tioconazole

Drugs.com:http://www.drugs.com/cdi/tioconazole.html

Drugs Product Database (DPD):2217406

RxList:http://www.rxlist.com/cgi/generic3/tioconaz.htm

http://purl.obolibrary.org/obo/dinto_000055