The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

laronidase

Synonyms
ID

http://purl.obolibrary.org/obo/dinto_DB00090

AHFScode

44:00.00

ATCCode

A16AB05

CASRN

210589-09-6

DBBrand

aldurazyme

DBSynonym

alpha-l-iduronidase precursor

Definition

Human recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology in a Chinese hamster ovary cell line. Laronidase is a glycoprotein with a molecular weight of approximately 83 kD. The predicted amino acid sequence of the recombinant form, as well as the nucleotide sequence that encodes it, are identical to a polymorphic form of human a-L-iduronidase. It contains 6 N-linked oligosaccharide modification sites.

has pharmacological target

http://purl.obolibrary.org/obo/dinto_2862

label

laronidase

prefixIRI

obo2:dinto_DB00090

prefLabel

laronidase

related with

http://purl.obolibrary.org/obo/dinto_2862

xref

Drugs Product Database (DPD):2254506

GenBank:M74715

PharmGKB:PA164776670

RxList:http://www.rxlist.com/cgi/generic3/aldurazyme.htm

Drugs.com:http://www.drugs.com/cdi/laronidase.html

UniProtKB:P35475

Wikipedia:http://en.wikipedia.org/wiki/Laronidase

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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