loading...| Preferred Name |
basiliximab |
|
| Synonyms |
|
|
| ID |
http://purl.obolibrary.org/obo/dinto_DB00074 |
|
| AHFScode |
92:00.00 |
|
| ATCCode |
L04AC02 |
|
| binds |
http://purl.obolibrary.org/obo/dinto_3109 http://purl.obolibrary.org/obo/dinto_3105 http://purl.obolibrary.org/obo/dinto_3106 http://purl.obolibrary.org/obo/dinto_3107 http://purl.obolibrary.org/obo/dinto_3078 http://purl.obolibrary.org/obo/dinto_3084 http://purl.obolibrary.org/obo/dinto_3112 http://purl.obolibrary.org/obo/dinto_3111 http://purl.obolibrary.org/obo/dinto_3709 http://purl.obolibrary.org/obo/dinto_3333 http://purl.obolibrary.org/obo/dinto_3339 |
|
| CASRN |
152923-56-3 |
|
| DBBrand |
simulect (novartis pharmaceuticals) |
|
| DBSynonym |
ig gamma-1 chain c region chimeric mouse-human anticd25 |
|
| Definition |
A recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also known as CD25 antigen) on the surface of activated T-lymphocytes. It is a 144 kDa glycoprotein obtained from fermentation of an established mouse myeloma cell line genetically engineered to express plasmids containing the human heavy and light chain constant region genes and mouse heavy and light chain variable region genes encoding the RFT5 antibody that binds selectively to the IL-2R alpha. |
|
| has pharmacological target | ||
| label |
basiliximab |
|
| may interact with |
http://purl.obolibrary.org/obo/dinto_DB06372 |
|
| prefixIRI |
obo2:dinto_DB00074 |
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| prefLabel |
basiliximab |
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| related with |
http://purl.obolibrary.org/obo/dinto_3109 http://purl.obolibrary.org/obo/dinto_3105 http://purl.obolibrary.org/obo/dinto_3106 http://purl.obolibrary.org/obo/dinto_3107 http://purl.obolibrary.org/obo/dinto_3078 http://purl.obolibrary.org/obo/dinto_3084 http://purl.obolibrary.org/obo/dinto_3112 http://purl.obolibrary.org/obo/dinto_3111 http://purl.obolibrary.org/obo/dinto_3709 http://purl.obolibrary.org/obo/dinto_3333 http://purl.obolibrary.org/obo/dinto_3339 |
|
| xref |
GenBank:J00228 Drugs.com:http://www.drugs.com/cdi/basiliximab.html National Drug Code Directory:0078-0393-61 Drugs Product Database (DPD):2242815 Wikipedia:http://en.wikipedia.org/wiki/Basiliximab UniProtKB:P01857 RxList:http://www.rxlist.com/cgi/generic2/basiliximab.htm PharmGKB:PA164747126 |
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| subClassOf |