The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

prednisolone

Synonyms

prednisolone

Delta(1)-dehydrocortisol

11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione

C21H28O5

prednisolonum

Delta(1)-dehydrohydrocortisone

(11beta)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione

1,4-pregnadiene-11beta,17alpha,21-triol-3,20-dione

1,4-pregnadiene-3,20-dione-11beta,17alpha,21-triol

3,20-dioxo-11beta,17alpha,21-trihydroxy-1,4-pregnadiene

hydroretrocortine

Delta(1)-hydrocortisone

metacortandralone

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one

prednisolona

ID

http://purl.obolibrary.org/obo/CHEBI_8378

activates

http://purl.obolibrary.org/obo/dinto_2874

AHFScode

52:08.08

68:04.00

ATCCode

D07AC14

S01CB02

D07AA01

S02BA03

R01AD02

C05AA04

S01BA04

H02AB07

D10AA02

A07EA01

S03BA02

D07XA02

H02AB06

D07AA03

H02AB04

binds

http://purl.obolibrary.org/obo/dinto_2146

CASRN

50-24-8

DBBrand

scherisolon

ak-tate

meti-derm

prednicen

lite pred

predcor-tba

hostacortin h

hydeltra-tba

delta-stab

ocu-pred

pred mild

hydrodeltisone

delta-cortef

delta f

predate tba

inflamase forte

paracortol

estilsona

derpo pd

supercortisol

flamasone

ultracorten h

fernisolone-p

ultracortene-h

dicortol

alphadrol

donisolone

erbacort

paracotol

meticortelone

metreton

predcor-50

deltacortenol

cordrol

fernisolone p

di-adreson f

cortalone

predalone t.b.a.

deltacortril enteric

cotolone

predonin

sterane

predniliderm

pediapred

hydeltra

eazolin d

hydeltrone

deltisilone

nor-pred t.b.a.

dydeltrone

predni-dome

rolisone

delcortol

predair forte

cotogesic

sterolone

dexa-cortidelt hostacortin h

ulacort

pred forte

deltacortril

key-pred

steran

predonine

precortancyl

solone

deltasolone

fernisolone

prenolone

hydroretrocortin

i-pred

hydroretrocortine

decortin h

ultracortene h

panafcortelone

ultra pred

predniretard

orapred

prednelan

lentosone

ocu-pred forte

ak-pred

predcor-25

m-predrol

klismacort

erbasona

prelone

co-hydeltra

precortilon

ophtho-tate

precortisyl

hydeltrasol

inflamase mild

medrol acetate

econopred

metacortandralone

depo-medrol

medrol

predne-dome

ultracortene-hydrogen

predair a

hydrodeltalone

decaprednil

prednis

precortalon

codelcortone

predair

predate-50

articulose-50

DBname

prednisolone

DBSynonym

prednisolone sodium phosphate

predisolone sodium phosphate

prednisolona [inn-spanish]

prednisolone acetate

deltahydrocortisone

prednisolone tebutate

prdl

prednisolonum [inn-latin]

methylprednisolone acetate

Definition

A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group.

has effect

http://purl.obolibrary.org/obo/OAE_0001078

http://purl.obolibrary.org/obo/OAE_0000355

http://purl.obolibrary.org/obo/OAE_0001101

http://purl.obolibrary.org/obo/OAE_0000400

http://purl.obolibrary.org/obo/OAE_0000390

http://purl.obolibrary.org/obo/OAE_0000401

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0001345

http://purl.obolibrary.org/obo/OAE_0000589

http://purl.obolibrary.org/obo/OAE_0000218

http://purl.obolibrary.org/obo/OAE_0001509

http://purl.obolibrary.org/obo/OAE_0001035

http://purl.obolibrary.org/obo/OAE_0000333

http://purl.obolibrary.org/obo/OAE_0001070

http://purl.obolibrary.org/obo/OAE_0001280

http://purl.obolibrary.org/obo/OAE_0001291

http://purl.obolibrary.org/obo/OAE_0001449

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000197

http://purl.obolibrary.org/obo/OAE_0000489

http://purl.obolibrary.org/obo/OAE_0000789

http://purl.obolibrary.org/obo/OAE_0000312

http://purl.obolibrary.org/obo/OAE_0000418

http://purl.obolibrary.org/obo/OAE_0001234

http://purl.obolibrary.org/obo/OAE_0000501

http://purl.obolibrary.org/obo/OAE_0000780

http://purl.obolibrary.org/obo/OAE_0000306

http://purl.obolibrary.org/obo/OAE_0001468

http://purl.obolibrary.org/obo/OAE_0000630

http://purl.obolibrary.org/obo/OAE_0001744

http://purl.obolibrary.org/obo/OAE_0002206

http://purl.obolibrary.org/obo/OAE_0001515

http://purl.obolibrary.org/obo/OAE_0000492

http://purl.obolibrary.org/obo/OAE_0001481

http://purl.obolibrary.org/obo/OAE_0000469

http://purl.obolibrary.org/obo/OAE_0000785

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0001276

http://purl.obolibrary.org/obo/OAE_0000195

http://purl.obolibrary.org/obo/OAE_0000403

http://purl.obolibrary.org/obo/OAE_0000460

http://purl.obolibrary.org/obo/OAE_0000243

http://purl.obolibrary.org/obo/OAE_0000454

http://purl.obolibrary.org/obo/OAE_0000038

http://purl.obolibrary.org/obo/OAE_0001073

http://purl.obolibrary.org/obo/OAE_0000660

http://purl.obolibrary.org/obo/OAE_0000525

http://purl.obolibrary.org/obo/OAE_0000779

http://purl.obolibrary.org/obo/OAE_0000466

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0001529

has pharmacological target

http://purl.obolibrary.org/obo/dinto_2874

has role

http://purl.obolibrary.org/obo/CHEBI_35705

http://purl.obolibrary.org/obo/CHEBI_35610

http://purl.obolibrary.org/obo/CHEBI_35472

http://purl.obolibrary.org/obo/CHEBI_37962

InChI

InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

InChIKey

InChIKey=OIGNJSKKLXVSLS-VWUMJDOOSA-N

inhibits

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_1987

http://purl.obolibrary.org/obo/dinto_2496

is metabolised by

http://purl.obolibrary.org/obo/dinto_0901

is transported by

http://purl.obolibrary.org/obo/dinto_1440

label

prednisolone

may interact with

http://purl.obolibrary.org/obo/dinto_DB01294

http://purl.obolibrary.org/obo/CHEBI_9073

http://purl.obolibrary.org/obo/dinto_DB01346

http://purl.obolibrary.org/obo/dinto_DB01397

http://purl.obolibrary.org/obo/dinto_DB00237

http://purl.obolibrary.org/obo/CHEBI_10033

http://purl.obolibrary.org/obo/dinto_DB01399

http://purl.obolibrary.org/obo/dinto_DB01320

http://purl.obolibrary.org/obo/CHEBI_3641

http://purl.obolibrary.org/obo/dinto_DB01398

http://purl.obolibrary.org/obo/dinto_DB00286

http://purl.obolibrary.org/obo/dinto_DB00312

http://purl.obolibrary.org/obo/CHEBI_4513

http://purl.obolibrary.org/obo/CHEBI_28077

http://purl.obolibrary.org/obo/CHEBI_251408

http://purl.obolibrary.org/obo/dinto_DB01341

http://purl.obolibrary.org/obo/dinto_DB00783

http://purl.obolibrary.org/obo/dinto_DB00794

http://purl.obolibrary.org/obo/CHEBI_6758

http://purl.obolibrary.org/obo/dinto_DB00977

http://purl.obolibrary.org/obo/dinto_DB01026

http://purl.obolibrary.org/obo/dinto_DB00382

http://purl.obolibrary.org/obo/CHEBI_3752

http://purl.obolibrary.org/obo/CHEBI_41922

http://purl.obolibrary.org/obo/dinto_DB04575

http://purl.obolibrary.org/obo/dinto_DB01167

http://purl.obolibrary.org/obo/dinto_DB04574

http://purl.obolibrary.org/obo/dinto_DB01357

http://purl.obolibrary.org/obo/dinto_DB01122

http://purl.obolibrary.org/obo/dinto_DB01353

http://purl.obolibrary.org/obo/CHEBI_7514

http://purl.obolibrary.org/obo/dinto_DB01355

http://purl.obolibrary.org/obo/dinto_DB01352

http://purl.obolibrary.org/obo/CHEBI_133809

http://purl.obolibrary.org/obo/CHEBI_102524

http://purl.obolibrary.org/obo/dinto_DB01401

http://purl.obolibrary.org/obo/dinto_DB01354

http://purl.obolibrary.org/obo/dinto_DB00306

http://purl.obolibrary.org/obo/dinto_DB04573

http://purl.obolibrary.org/obo/CHEBI_15365

http://purl.obolibrary.org/obo/CHEBI_17263

http://purl.obolibrary.org/obo/dinto_DB00072

http://purl.obolibrary.org/obo/dinto_DB00545

http://purl.obolibrary.org/obo/dinto_DB00532

http://purl.obolibrary.org/obo/dinto_DB01351

http://purl.obolibrary.org/obo/CHEBI_53766

http://purl.obolibrary.org/obo/CHEBI_8069

http://purl.obolibrary.org/obo/CHEBI_102216

http://purl.obolibrary.org/obo/CHEBI_8107

http://purl.obolibrary.org/obo/CHEBI_9939

http://purl.obolibrary.org/obo/CHEBI_4888

http://purl.obolibrary.org/obo/CHEBI_6933

prefixIRI

obo2:CHEBI_8378

prefLabel

prednisolone

SMILES

[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]1(C)[C@@]2([H])CC[C@]1(O)C(=O)CO

[H][C@@]12CC[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C=C[C@]12C

Synonym

prednisolone

Delta(1)-dehydrocortisol

11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione

C21H28O5

prednisolonum

Delta(1)-dehydrohydrocortisone

(11beta)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione

1,4-pregnadiene-11beta,17alpha,21-triol-3,20-dione

1,4-pregnadiene-3,20-dione-11beta,17alpha,21-triol

3,20-dioxo-11beta,17alpha,21-trihydroxy-1,4-pregnadiene

hydroretrocortine

Delta(1)-hydrocortisone

metacortandralone

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one

prednisolona

xref

DrugBank:DB00860

CASRN:50-24-8

Drugs Product Database (DPD):2245532

ChemSpider:5552

Wikipedia:Prednisolone

Wikipedia:http://en.wikipedia.org/wiki/Prednisolone

PubChem Compound:5755

HMDB:HMDB14998

PubChem Substance:46504847

ChEMBL:127370

PharmGKB:PA451096

RxList:http://www.rxlist.com/cgi/generic/prednisolone.htm

Guide To Pharmacology:2866

Drugs.com:http://www.drugs.com/cdi/prednisolone-acetate-drops.html

ChEBI:8378

National Drug Code Directory:0121-0687-05

CASRN:1354103

IUPHAR:2866

KEGG DRUG:D00472

BindingDB:19190

KEGG COMPOUND:C07369

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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http://purl.bioontology.org/ontology/NDFRT/N0000146334 NDFRT LOOM
http://purl.bioontology.org/ontology/VANDF/4017988 VANDF LOOM
http://purl.bioontology.org/ontology/UATC/R01AD02 ATC LOOM
http://purl.bioontology.org/ontology/UATC/S01BA04 ATC LOOM
http://www.co-ode.org/ontologies/galen#Prednisolone GALEN LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#10042 OCHV LOOM
http://purl.bioontology.org/ontology/UATC/S03BA02 ATC LOOM
http://purl.jp/bio/4/id/200906036005597987 IOBC LOOM
http://purl.bioontology.org/ontology/RXNORM/8638 RXNORM LOOM
http://purl.bioontology.org/ontology/LNC/MTHU003522 LOINC LOOM
http://webprotege.stanford.edu/RMLTPoYQg83oLCbnC9p0or COPDO LOOM
http://purl.bioontology.org/ontology/UATC/H02AB06 ATC LOOM
http://stirdf.jst.go.jp/id/200907039479477055 IOBC LOOM
http://purl.bioontology.org/ontology/MESH/D011239 MESH LOOM
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http://purl.bioontology.org/ontology/PDQ/CDR0000043296 PDQ LOOM
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http://purl.bioontology.org/ontology/NDDF/002155 NDDF LOOM
http://purl.bioontology.org/ontology/UATC/C05AA04 ATC LOOM
http://purl.bioontology.org/ontology/UATC/A07EA01 ATC LOOM
http://scai.fraunhofer.de/MSOntology#Prednisolone MSO LOOM
http://purl.obolibrary.org/obo/CHEBI_8378 ODNAE LOOM
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http://purl.obolibrary.org/obo/CHEBI_8378 NIFSTD LOOM
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http://www.drugbank.ca/drugs/DB00860 FTC LOOM
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http://purl.obolibrary.org/obo/DDO.owl#DDO_0004532 DDO LOOM
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http://purl.bioontology.org/ontology/UATC/S01CB02 ATC LOOM
http://purl.bioontology.org/ontology/UATC/D07AA03 ATC LOOM
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