loading...| Preferred Name |
glimepiride |
|
| Synonyms |
3-ethyl-4-methyl-N-{2-[4-({[(4-methylcyclohexyl)carbamoyl]amino}sulfonyl)phenyl]ethyl}-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide 1-((p-(2-(3-Ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl)phenyl)sulfonyl)-3-(trans-4-methylcyclohexyl)urea glimepiridum 3-ethyl-4-methyl-N-[2-(4-{[(trans-4-methylcyclohexyl)carbamoyl]sulfamoyl}phenyl)ethyl]-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide C24H34N4O5S gimepiride Amaryl glimepiride 1-{[4-(2-{[(3-ethyl-4-methyl-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)carbonyl]amino}ethyl)phenyl]sulfonyl}-3-(trans-4-methylcyclohexyl)urea glimepirida |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_5383 |
|
| AHFScode |
68:20.20 |
|
| ATCCode |
A10BB12 |
|
| binds |
http://purl.obolibrary.org/obo/dinto_3338 http://purl.obolibrary.org/obo/dinto_3464 |
|
| CASRN |
93479-97-1 |
|
| DBBrand |
pms-glimepiride sandoz glimepiride ratio-glimepiride novo-glimepiride amarel endial amaryl |
|
| DBname |
glimepiride |
|
| DBSynonym |
glimepride glimepirid glimepiridum glimepirida |
|
| Definition |
A N-acylurea that has formula C24H34N4O5S. |
|
| has effect |
http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000210 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000050 http://purl.obolibrary.org/obo/OAE_0001026 http://purl.obolibrary.org/obo/OAE_0000287 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0001275 http://purl.obolibrary.org/obo/OAE_0001295 http://purl.obolibrary.org/obo/OAE_0000268 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0000022 http://purl.obolibrary.org/obo/OAE_0000468 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000565 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0001309 |
|
| has pharmacological target |
http://purl.obolibrary.org/obo/dinto_2142 |
|
| has role | ||
| InChI |
InChI=1S/C24H34N4O5S/c1-4-21-17(3)15-28(22(21)29)24(31)25-14-13-18-7-11-20(12-8-18)34(32,33)27-23(30)26-19-9-5-16(2)6-10-19/h7-8,11-12,16,19H,4-6,9-10,13-15H2,1-3H3,(H,25,31)(H2,26,27,30) InChI=1S/C24H34N4O5S/c1-4-21-17(3)15-28(22(21)29)24(31)25-14-13-18-7-11-20(12-8-18)34(32,33)27-23(30)26-19-9-5-16(2)6-10-19/h7-8,11-12,16,19H,4-6,9-10,13-15H2,1-3H3,(H,25,31)(H2,26,27,30)/t16-,19- |
|
| InChIKey |
InChIKey=WIGIZIANZCJQQY-RUCARUNLSA-N InChIKey=WIGIZIANZCJQQY-UHFFFAOYSA-N |
|
| induces | ||
| inhibits | ||
| is metabolised by | ||
| is substrate of | ||
| label |
glimepiride |
|
| may interact with |
http://purl.obolibrary.org/obo/CHEBI_5296 http://purl.obolibrary.org/obo/dinto_DB01296 http://purl.obolibrary.org/obo/CHEBI_4031 http://purl.obolibrary.org/obo/dinto_DB00052 http://purl.obolibrary.org/obo/dinto_DB01026 |
|
| prefixIRI |
obo2:CHEBI_5383 |
|
| prefLabel |
glimepiride |
|
| SMILES |
CCC1=C(C)CN(C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC2CCC(C)CC2)C1=O CCC1=C(C)CN(C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)N[C@H]2CC[C@H](C)CC2)C1=O |
|
| Synonym |
3-ethyl-4-methyl-N-{2-[4-({[(4-methylcyclohexyl)carbamoyl]amino}sulfonyl)phenyl]ethyl}-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide 1-((p-(2-(3-Ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl)phenyl)sulfonyl)-3-(trans-4-methylcyclohexyl)urea glimepiridum 3-ethyl-4-methyl-N-[2-(4-{[(trans-4-methylcyclohexyl)carbamoyl]sulfamoyl}phenyl)ethyl]-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide C24H34N4O5S gimepiride Amaryl glimepiride 1-{[4-(2-{[(3-ethyl-4-methyl-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)carbonyl]amino}ethyl)phenyl]sulfonyl}-3-(trans-4-methylcyclohexyl)urea glimepirida |
|
| xref |
ChEBI:5383 PharmGKB:PA449761 KEGG COMPOUND:C07669 Wikipedia:http://en.wikipedia.org/wiki/Glimepiride CiteXplore:12369756 Drugs.com:http://www.drugs.com/cdi/glimepiride.html ChemSpider:3357 CiteXplore:11199230 CASRN:93479-97-1 Reaxys:7731873 CiteXplore:23305037 PubChem Compound:3476 PubChem Substance:46508842 DrugBank:DB00222 HMDB:HMDB14367 RxList:http://www.rxlist.com/cgi/generic/glimepiride.htm National Drug Code Directory:61442-115-01 KEGG DRUG:D00593 CiteXplore:22469262 CiteXplore:8141820 ChEMBL:505366 CiteXplore:12852703 Drugs Product Database (DPD):2245274 |
|
| subClassOf |