The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

famciclovir

Synonyms

FCV

C14H19N5O4

BRL-42810

famciclovir

famciclovirum

FAMCICLOVIR

2-(2-(2-amino-9H-purin-9-yl)ethyl)-1,3-propanediol diacetate

Famvir

2-[(acetyloxy)methyl]-4-(2-amino-9H-purin-9-yl)butyl acetate

9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine

acetic acid 2-acetoxymethyl-4-(2-amino-purin-9-yl)-butyl ester

ID

http://purl.obolibrary.org/obo/CHEBI_4974

AHFScode

08:18.32

altId

CHEBI:174284

ATCCode

S01AD07

J05AB09

CASRN

104227-87-4

DBBrand

famvir

DBname

famciclovir

DBSynonym

fcv

famciclovirum [inn-latin]

Definition

2-Amino-9H-purine in which the hydrogen at position 9 is substituted by a 4-acetoxy-3-(acetoxymethyl)but-1-yl group. A prodrug of the antiviral penciclovir, it is used for the treatment of acute herpes zoster (shingles), for the treatment or suppression of recurrent genital herpes in immunocompetent patients and for the treatment of recurrent mucocutaneous herpes simplex infections in HIV infected patients.

has effect

http://purl.obolibrary.org/obo/OAE_0000505

http://purl.obolibrary.org/obo/OAE_0001425

http://purl.obolibrary.org/obo/OAE_0000401

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0001106

http://purl.obolibrary.org/obo/OAE_0001129

http://purl.obolibrary.org/obo/OAE_0000449

http://purl.obolibrary.org/obo/OAE_0000391

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0001025

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000396

http://purl.obolibrary.org/obo/OAE_0000468

http://purl.obolibrary.org/obo/OAE_0000512

http://purl.obolibrary.org/obo/OAE_0000479

http://purl.obolibrary.org/obo/OAE_0001364

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0001217

http://purl.obolibrary.org/obo/OAE_0001463

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000645

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0000881

http://purl.obolibrary.org/obo/OAE_0000602

http://purl.obolibrary.org/obo/OAE_0000536

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0001365

http://purl.obolibrary.org/obo/OAE_0000607

has pharmacological target

http://purl.obolibrary.org/obo/dinto_3977

http://purl.obolibrary.org/obo/dinto_1107

has role

http://purl.obolibrary.org/obo/CHEBI_50266

http://purl.obolibrary.org/obo/CHEBI_36044

InChI

InChI=1S/C14H19N5O4/c1-9(20)22-6-11(7-23-10(2)21)3-4-19-8-17-12-5-16-14(15)18-13(12)19/h5,8,11H,3-4,6-7H2,1-2H3,(H2,15,16,18)

InChIKey

InChIKey=GGXKWVWZWMLJEH-UHFFFAOYSA-N

inhibits

http://purl.obolibrary.org/obo/dinto_3977

http://purl.obolibrary.org/obo/dinto_1107

is metabolised by

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_0273

label

famciclovir

prefixIRI

obo2:CHEBI_4974

prefLabel

famciclovir

SMILES

CC(=O)OCC(CCn1cnc2cnc(N)nc12)COC(C)=O

CC(=O)OCC(CCN1C=NC2=CN=C(N)N=C12)COC(C)=O

Synonym

FCV

C14H19N5O4

BRL-42810

famciclovir

famciclovirum

FAMCICLOVIR

2-(2-(2-amino-9H-purin-9-yl)ethyl)-1,3-propanediol diacetate

Famvir

2-[(acetyloxy)methyl]-4-(2-amino-9H-purin-9-yl)butyl acetate

9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine

acetic acid 2-acetoxymethyl-4-(2-amino-purin-9-yl)-butyl ester

xref

KEGG DRUG:D00317

Wikipedia:Famciclovir

National Drug Code Directory:0078-0366-15

CASRN:104227-87-4

PubChem Compound:3324

PubChem Substance:46507561

ChEMBL:17870541

BindingDB:50066502

Drugs.com:http://www.drugs.com/cdi/famciclovir.html

Wikipedia:http://en.wikipedia.org/wiki/Famciclovir

ChEMBL:9719596

DrugBank:DB00426

ChemSpider:3207

Patent:US5246937

ChEBI:4974

Drugs Product Database (DPD):2229110

HMDB:HMDB14570

RxList:http://www.rxlist.com/cgi/generic3/famciclovir.htm

ChEMBL:2754699

Reaxys:4208403

PharmGKB:PA449585

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29044 NCIT LOOM
http://purl.jp/bio/4/id/200906085346025605 IOBC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148380 NDFRT LOOM
http://purl.bioontology.org/ontology/SNMI/C-55B14 SNMI LOOM
http://purl.bioontology.org/ontology/MESH/D000077595 MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/68099 RXNORM LOOM
http://purl.bioontology.org/ontology/UATC/S01AD07 ATC LOOM
http://purl.obolibrary.org/obo/CHEBI_4974 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_4974 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4974 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4974 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4974 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_4974 DRON SAME_URI
http://purl.bioontology.org/ontology/LNC/LP157326-2 LOINC LOOM
http://www.co-ode.org/ontologies/galen#Famciclovir GALEN LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C060590 RH-MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4020882 VANDF LOOM
http://purl.bioontology.org/ontology/UATC/J05AB09 ATC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU045606 LOINC LOOM
http://stirdf.jst.go.jp/id/200907093494886110 IOBC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387557001 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/NDDF/004470 NDDF LOOM