The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
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Preferred Name

ezetimibe
Synonyms

Zetia

Ezedoc

ezetimiba

(3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one

ezetimibum

ezetimibe

Ezetrol

C24H21F2NO3
ID

http://purl.obolibrary.org/obo/CHEBI_49040
AHFScode

24:06.05
ATCCode

C10AX09
binds

http://purl.obolibrary.org/obo/dinto_2885

http://purl.obolibrary.org/obo/dinto_2775

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_0822

http://purl.obolibrary.org/obo/dinto_1890

http://purl.obolibrary.org/obo/dinto_1892

http://purl.obolibrary.org/obo/dinto_1711

http://purl.obolibrary.org/obo/dinto_0276

http://purl.obolibrary.org/obo/dinto_0588

http://purl.obolibrary.org/obo/dinto_0887

http://purl.obolibrary.org/obo/dinto_0883

http://purl.obolibrary.org/obo/dinto_1560

http://purl.obolibrary.org/obo/dinto_1561

http://purl.obolibrary.org/obo/dinto_2019

http://purl.obolibrary.org/obo/dinto_1440
CASRN

163222-33-1
DBBrand

ezedoc

zient

zetia

maxetibe

zetavim

zemitra

ezetib

ezetrol
DBname

ezetimibe
Definition

A beta-lactam that is azetidin-2-one which is substituted at 1, 3, and 4 by p-fluorophenyl, 3-(p-fluorophenyl)-3-hydroxypropyl, and 4-hydroxyphenyl groups, respectively (the 3R,3'S,4S enantiomer).
has effect

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000449

http://purl.obolibrary.org/obo/OAE_0001373

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000839

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0000406

http://purl.obolibrary.org/obo/OAE_0001369

http://purl.obolibrary.org/obo/OAE_0000567

http://purl.obolibrary.org/obo/OAE_0000195

http://purl.obolibrary.org/obo/OAE_0000210

http://purl.obolibrary.org/obo/OAE_0000319

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0001378

http://purl.obolibrary.org/obo/OAE_0000375

http://purl.obolibrary.org/obo/OAE_0000455

http://purl.obolibrary.org/obo/OAE_0000645

http://purl.obolibrary.org/obo/OAE_0000584

http://purl.obolibrary.org/obo/OAE_0000414

http://purl.obolibrary.org/obo/OAE_0000525

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0000343

http://purl.obolibrary.org/obo/OAE_0000022

http://purl.obolibrary.org/obo/OAE_0000385

http://purl.obolibrary.org/obo/OAE_0000336

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000466

http://purl.obolibrary.org/obo/OAE_0000358

http://purl.obolibrary.org/obo/OAE_0000402
has pharmacological target

http://purl.obolibrary.org/obo/dinto_2885

http://purl.obolibrary.org/obo/dinto_2775
has role

http://purl.obolibrary.org/obo/CHEBI_35679

http://purl.obolibrary.org/obo/CHEBI_35821

http://purl.obolibrary.org/obo/CHEBI_35221
InChI

InChI=1S/C24H21F2NO3/c25-17-5-1-15(2-6-17)22(29)14-13-21-23(16-3-11-20(28)12-4-16)27(24(21)30)19-9-7-18(26)8-10-19/h1-12,21-23,28-29H,13-14H2/t21-,22+,23-/m1/s1
InChIKey

InChIKey=OLNTVTPDXPETLC-XPWALMASSA-N
inhibits

http://purl.obolibrary.org/obo/dinto_2885

http://purl.obolibrary.org/obo/dinto_2775

http://purl.obolibrary.org/obo/dinto_0901
is metabolised by

http://purl.obolibrary.org/obo/dinto_1890

http://purl.obolibrary.org/obo/dinto_1892

http://purl.obolibrary.org/obo/dinto_1711

http://purl.obolibrary.org/obo/dinto_0276
is substrate of

http://purl.obolibrary.org/obo/dinto_1890

http://purl.obolibrary.org/obo/dinto_1892

http://purl.obolibrary.org/obo/dinto_1711

http://purl.obolibrary.org/obo/dinto_0276

http://purl.obolibrary.org/obo/dinto_0588

http://purl.obolibrary.org/obo/dinto_0887

http://purl.obolibrary.org/obo/dinto_0883

http://purl.obolibrary.org/obo/dinto_1560

http://purl.obolibrary.org/obo/dinto_1561

http://purl.obolibrary.org/obo/dinto_2019

http://purl.obolibrary.org/obo/dinto_1440
is transported by

http://purl.obolibrary.org/obo/dinto_0588

http://purl.obolibrary.org/obo/dinto_0887

http://purl.obolibrary.org/obo/dinto_0883

http://purl.obolibrary.org/obo/dinto_1560

http://purl.obolibrary.org/obo/dinto_1561

http://purl.obolibrary.org/obo/dinto_2019

http://purl.obolibrary.org/obo/dinto_1440
label

ezetimibe
may interact with

http://purl.obolibrary.org/obo/CHEBI_4031

http://purl.obolibrary.org/obo/CHEBI_10033

http://purl.obolibrary.org/obo/dinto_DB01432
prefixIRI

obo2:CHEBI_49040
prefLabel

ezetimibe
related with

http://purl.obolibrary.org/obo/dinto_0822
SMILES

[H][C@]1(CC[C@H](O)c2ccc(F)cc2)C(=O)N(c2ccc(F)cc2)[C@]1([H])c1ccc(O)cc1

O[C@@H](CC[C@@H]1[C@H](N(C1=O)C1=CC=C(F)C=C1)C1=CC=C(O)C=C1)C1=CC=C(F)C=C1
Synonym

Zetia

Ezedoc

ezetimiba

(3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one

ezetimibum

ezetimibe

Ezetrol

C24H21F2NO3
xref

RxList:http://www.rxlist.com/cgi/generic/ezetimibe.htm

PubChem Substance:46507625

DrugBank:DB00973

CiteXplore:23317398

CiteXplore:23510093

Drugs Product Database (DPD):2247521

Reaxys:7981967

CiteXplore:23538020

ChemSpider:132493

CiteXplore:18585981

Beilstein:7981967

ChEMBL:275106

PubChem Compound:150311

HMDB:HMDB15108

CiteXplore:23471229

CiteXplore:23266293

Wikipedia:Ezetimibe

CiteXplore:17587760

PharmGKB:PA10816

KEGG DRUG:D01966

Drugs.com:http://www.drugs.com/ezetimibe.html

CASRN:163222-33-1

Wikipedia:http://en.wikipedia.org/wiki/Ezetimibe

CiteXplore:23219178

National Drug Code Directory:66582-414-31

ChEBI:49040
subClassOf

http://purl.obolibrary.org/obo/dinto_000055
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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_49040 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_49040 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_49040 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_49040 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_49040 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_49040 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_49040 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/CHEBI_49040 HINO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_49040 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_49040 CHEBI LOOM
http://purl.bioontology.org/ontology/MESH/D000069438 MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4021366 VANDF LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C1142985 OCHV LOOM
http://www.phoc.org.cn/pmo/class/PMO_00018150 PMAPP-PMO LOOM
http://purl.obolibrary.org/obo/MESH_D000069438 BERO LOOM
http://purl.bioontology.org/ontology/ATC/C10AX09 ATC LOOM
http://www.ustb.edu.cn/thesauri/tocr/v1/data#C571353432175145040 ACVD_ONTOLOGY LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148785 OCVDAE LOOM
http://bmi.utah.edu/ontologies/peontology/C1142985 RAO LOOM
http://purl.obolibrary.org/obo/OMIT_0001428 OMIT LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148785 NDFRT LOOM
http://www.drugbank.ca/drugs/DB00973 FTC LOOM
http://purl.jp/bio/4/id/200906018375117374 IOBC LOOM
https://go.drugbank.com/drugs/DB00973 MDM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C108606 RH-MESH LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000754008 PDQ LOOM
http://purl.obolibrary.org/obo/NCIT_C47529 BERO LOOM
http://stirdf.jst.go.jp/id/200907074949452186 IOBC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/409149001 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/LNC/LP171397-5 LOINC LOOM
http://purl.obolibrary.org/obo/CHEBI_49040 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_49040 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_49040 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_49040 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_49040 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_49040 HINO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47529 NCIT LOOM
http://purl.bioontology.org/ontology/NDDF/009817 NDDF LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#55188 OCHV LOOM
http://purl.bioontology.org/ontology/RXNORM/341248 RXNORM LOOM
http://www.semanticweb.org/ontologies/STO.owl#eeaaa81c_c419_4c2f_9d0a_bdc37fcac775 STO-DRAFT LOOM
http://www.semanticweb.org/ontologies/STO.owl#eeaaa81c_c419_4c2f_9d0a_bdc37fcac775 CVAO LOOM