The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

dezocine

Synonyms

(1R,9S,15S)-15-amino-1-methyltricyclo[7.5.1.0^{2,7}]pentadeca-2,4,6-trien-4-ol

(5R,11S,13S)-13-amino-5-methyl-5,6,7,8,9,10,11,12-octahydro-5,11-methanobenzocyclodecen-3-ol

dezocine

C16H23NO

dezocinum

dezocina

Dezocine

(-)-13beta-amino-5,6,7,8,9,10,11alpha,12-octahydro-5alpha-methyl-5,11-methanobenzocyclodecen-3-ol

ID

http://purl.obolibrary.org/obo/CHEBI_4474

activates

http://purl.obolibrary.org/obo/dinto_2787

altId

CHEBI:618361

ATCCode

N02AX03

blocks

http://purl.obolibrary.org/obo/dinto_3960

CASRN

53648-55-8

DBBrand

dalgan

DBname

dezocine

DBSynonym

dezocinum [inn-latin]

dezocina [inn-spanish]

Definition

(7S,8S)-7-Amino-8-methyl-5,6,7,8-tetrahydronaphthalen-2-ol in which the hydrogen at position 8 and one of the hydrogens at position 6 are substituted by each end of a tetramethylene bridge. A synthetic opioid analgesic, it has mixed opiod agonist and antagonist properties. Although it is used for pain management, it can produce opioid withdrawal syndrome in patients already dependent on other opioids, and its clinical application is limited by side effects such as dizziness.

has pharmacological target

http://purl.obolibrary.org/obo/dinto_3960

http://purl.obolibrary.org/obo/dinto_2787

has role

http://purl.obolibrary.org/obo/CHEBI_35482

InChI

InChI=1S/C16H23NO/c1-16-8-4-2-3-5-12(15(16)17)9-11-6-7-13(18)10-14(11)16/h6-7,10,12,15,18H,2-5,8-9,17H2,1H3/t12-,15-,16+/m0/s1

InChIKey

InChIKey=VTMVHDZWSFQSQP-VBNZEHGJSA-N

label

dezocine

may interact with

http://purl.obolibrary.org/obo/dinto_DB00427

http://purl.obolibrary.org/obo/dinto_DB06274

prefixIRI

obo2:CHEBI_4474

prefLabel

dezocine

SMILES

[H][C@@]12CCCCC[C@@](C)([C@H]1N)c1cc(O)ccc1C2

[H][C@@]12CC3=CC=C(O)C=C3[C@@](C)(CCCCC1)[C@H]2N

Synonym

(1R,9S,15S)-15-amino-1-methyltricyclo[7.5.1.0^{2,7}]pentadeca-2,4,6-trien-4-ol

(5R,11S,13S)-13-amino-5-methyl-5,6,7,8,9,10,11,12-octahydro-5,11-methanobenzocyclodecen-3-ol

dezocine

C16H23NO

dezocinum

dezocina

Dezocine

(-)-13beta-amino-5,6,7,8,9,10,11alpha,12-octahydro-5alpha-methyl-5,11-methanobenzocyclodecen-3-ol

xref

DrugBank:DB01209

KEGG DRUG:D00838

KEGG COMPOUND:C08010

ChEBI:4474

CASRN:53648-55-8

Patent:DE2159324

PharmGKB:PA164746059

Wikipedia:Dezocine

Beilstein:3033759

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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http://www.drugbank.ca/drugs/DB01209 FTC LOOM
http://purl.obolibrary.org/obo/CHEBI_4474 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_4474 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4474 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4474 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4474 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4474 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4474 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4474 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4474 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4474 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4474 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4474 CHEBI SAME_URI
http://purl.bioontology.org/ontology/LNC/LP18550-1 LOINC LOOM
http://stirdf.jst.go.jp/id/200907019842073831 IOBC LOOM
http://stirdf.jst.go.jp/id/200907019842073831 IOBC LOOM
http://stirdf.jst.go.jp/id/200907019842073831 IOBC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147635 NDFRT LOOM
http://purl.bioontology.org/ontology/NDDF/003545 NDDF LOOM
http://purl.bioontology.org/ontology/VANDF/4019515 VANDF LOOM
http://purl.bioontology.org/ontology/MESH/C010827 MESH LOOM
http://purl.bioontology.org/ontology/LNC/MTHU004622 LOINC LOOM
http://purl.jp/bio/4/id/200906029605163216 IOBC LOOM
http://purl.jp/bio/4/id/200906029605163216 IOBC LOOM
http://purl.jp/bio/4/id/200906029605163216 IOBC LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65374 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65374 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65374 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65374 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65374 NCIT LOOM
http://purl.obolibrary.org/obo/DRON_00010596 DRON LOOM
http://purl.bioontology.org/ontology/UATC/N02AX03 ATC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/108377005 SNOMEDCT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C010827 RH-MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/22713 RXNORM LOOM