The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

tramadol hydrochloride

Synonyms

rac-(1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol hydrochloride

Tramadol HCl

(1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexan-1-ol

tramadol monohydrochloride

racemic tramadol hydrochloride

(+-)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol hydrochloride

C16H25NO2

(+-)-tramadol hydrochloride

C16H25NO2.HCl

ID

http://purl.obolibrary.org/obo/CHEBI_32250

activates

http://purl.obolibrary.org/obo/dinto_3960

http://purl.obolibrary.org/obo/dinto_0760

http://purl.obolibrary.org/obo/dinto_2787

AHFScode

28:08.08

altId

CHEBI:75732

ATCCode

N02AX02

blocks

http://purl.obolibrary.org/obo/dinto_2150

http://purl.obolibrary.org/obo/dinto_3364

http://purl.obolibrary.org/obo/dinto_1005

http://purl.obolibrary.org/obo/dinto_0510

CASRN

27203-92-5

DBBrand

ralivia er

ultram er

rybix

ralivia flashtab

tramadol hcl bp/ep

tridural

crispin

conzip

durela

ultram

tramal

zytram xl

DBname

tramadol

DBSalt

tramadol hydrochloride

Definition

A racemate consisting of equal amounts of (R,R)- and (S,S)-tramadol hydrochloride. A centrally acting synthetic opioid analgesic, used to treat moderately severe pain. The (R,R)-enantiomer exhibits ten-fold higher analgesic potency than the (S,S)-enantiomer.

has pharmacological target

http://purl.obolibrary.org/obo/dinto_0068

http://purl.obolibrary.org/obo/dinto_2714

http://purl.obolibrary.org/obo/dinto_2787

has role

http://purl.obolibrary.org/obo/CHEBI_70774

http://purl.obolibrary.org/obo/CHEBI_48279

http://purl.obolibrary.org/obo/CHEBI_60797

http://purl.obolibrary.org/obo/CHEBI_50949

http://purl.obolibrary.org/obo/CHEBI_51177

http://purl.obolibrary.org/obo/CHEBI_35640

http://purl.obolibrary.org/obo/CHEBI_55322

http://purl.obolibrary.org/obo/CHEBI_48876

http://purl.obolibrary.org/obo/CHEBI_64054

http://purl.obolibrary.org/obo/CHEBI_35482

http://purl.obolibrary.org/obo/CHEBI_48878

http://purl.obolibrary.org/obo/CHEBI_59282

InChI

InChI=1S/C16H25NO2/c1-17(2)12-14-7-4-5-10-16(14,18)13-8-6-9-15(11-13)19-3/h6,8-9,11,14,18H,4-5,7,10,12H2,1-3H3/t14-,16+/m1/s1

InChIKey

InChIKey=TVYLLZQTGLZFBW-ZBFHGGJFSA-N

inhibits

http://purl.obolibrary.org/obo/dinto_0068

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_2714

is metabolised by

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_0465

label

tramadol hydrochloride

prefixIRI

obo2:CHEBI_32250

prefLabel

tramadol hydrochloride

SMILES

COC1=CC=CC(=C1)[C@@]1(O)CCCC[C@@H]1CN(C)C

Synonym

rac-(1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol hydrochloride

Tramadol HCl

(1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexan-1-ol

tramadol monohydrochloride

racemic tramadol hydrochloride

(+-)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol hydrochloride

C16H25NO2

(+-)-tramadol hydrochloride

C16H25NO2.HCl

xref

Reaxys:6579261

CiteXplore:23363343

BindingDB:50176262

CiteXplore:22871232

CiteXplore:21950732

ChemSpider:31105

CiteXplore:24028179

CiteXplore:23249424

CiteXplore:23668411

PubChem Compound:33741

Wikipedia:Tramadol

Patent:US2013011444

CiteXplore:23103596

CASRN:36282-47-0

Wikipedia:http://en.wikipedia.org/wiki/Tramadol

CiteXplore:23802666

CiteXplore:23031839

CiteXplore:23428887

CiteXplore:23351340

CiteXplore:22918011

CiteXplore:22896821

CiteXplore:22959557

CiteXplore:23066205

CiteXplore:22674657

PubChem Substance:46506256

Reaxys:6640634

RxList:http://www.rxlist.com/cgi/generic/tramadol.htm

CiteXplore:23521170

CiteXplore:23029946

DrugBank:DB00193

National Drug Code Directory:0045-0659-60

Drugs.com:http://www.drugs.com/tramadol.html

PharmGKB:PA451735

CiteXplore:23789213

CiteXplore:23786206

CiteXplore:22849674

KEGG DRUG:D01355

Reaxys:9237274

CiteXplore:23203185

CiteXplore:23071920

CiteXplore:23724656

CiteXplore:24019801

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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http://www.co-ode.org/ontologies/galen#TramadolHydrochloride GALEN LOOM
http://purl.bioontology.org/ontology/RXNORM/82110 RXNORM LOOM
http://purl.obolibrary.org/obo/CHEBI_32250 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_32250 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_32250 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_32250 CHEBI SAME_URI
http://purl.bioontology.org/ontology/VANDF/4020912 VANDF LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148400 NDFRT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#27572 OCHV LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29508 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29508 NCIT LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/108505002 SNOMEDCT LOOM