loading...| Preferred Name |
benzthiazide |
|
| Synonyms |
benzotiazida 3-[(benzylsulfanyl)methyl]-6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide benzthiazide 3-benzylthiomethyl-6-chloro-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide C15H14ClN3O4S3 6-chloro-7-sulfamoyl-3-benzylthiomethyl-2H-1,2,4-benzothiadiazine 1,1-dioxide Benzthiazide 6-chloro-1,1-dioxo-3-(phenylmethylsulfanylmethyl)-4H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 3-((benzylthio)methyl)-6-chloro-7-sulfamoyl-2H-benzo-1,2,4-thiadiazine 1,1-dioxide benzothiazide 3-benzylthiomethyl-6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide benzthiazidum 3-[(benzylsulfanyl)methyl]-6-chloro-1,1-dioxo-4H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_3047 |
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| CASRN |
91-33-8 |
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| DBBrand |
urese naclex exosalt pfizer 1393 benzthazide edemex fovane exna proaqua diucen dihydrex benzothiazide lemazide hydrine aquatag freeuril |
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| DBname |
benzthiazide |
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| Definition |
7-Sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide in which the hydrogen at position 6 is substituted by chlorine and that at position 3 is substituted by a benzylsulfanylmethyl group. A diuretic, it is used to treat hypertension and edema. |
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| has pharmacological target | ||
| has role | ||
| InChI |
InChI=1S/C15H14ClN3O4S3/c16-11-6-12-14(7-13(11)25(17,20)21)26(22,23)19-15(18-12)9-24-8-10-4-2-1-3-5-10/h1-7H,8-9H2,(H,18,19)(H2,17,20,21) |
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| InChIKey |
InChIKey=NDTSRXAMMQDVSW-UHFFFAOYSA-N |
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| inhibits |
http://purl.obolibrary.org/obo/dinto_0512 http://purl.obolibrary.org/obo/dinto_0757 http://purl.obolibrary.org/obo/dinto_3399 http://purl.obolibrary.org/obo/dinto_1621 |
|
| label |
benzthiazide |
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| may interact with | ||
| prefixIRI |
obo2:CHEBI_3047 |
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| prefLabel |
benzthiazide |
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| SMILES |
NS(=O)(=O)c1cc2c(cc1Cl)N=C(CSCc1ccccc1)NS2(=O)=O NS(=O)(=O)C1=C(Cl)C=C2NC(CSCC3=CC=CC=C3)=NS(=O)(=O)C2=C1 |
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| Synonym |
benzotiazida 3-[(benzylsulfanyl)methyl]-6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide benzthiazide 3-benzylthiomethyl-6-chloro-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide C15H14ClN3O4S3 6-chloro-7-sulfamoyl-3-benzylthiomethyl-2H-1,2,4-benzothiadiazine 1,1-dioxide Benzthiazide 6-chloro-1,1-dioxo-3-(phenylmethylsulfanylmethyl)-4H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 3-((benzylthio)methyl)-6-chloro-7-sulfamoyl-2H-benzo-1,2,4-thiadiazine 1,1-dioxide benzothiazide 3-benzylthiomethyl-6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide benzthiazidum 3-[(benzylsulfanyl)methyl]-6-chloro-1,1-dioxo-4H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide |
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| xref |
PharmGKB:PA164776841 Patent:US3440244 ChemSpider:2253 ChEMBL:774990 PubChem Substance:46506752 CASRN:91-33-8 Beilstein:722681 KEGG DRUG:D00651 Patent:DE1137740 KEGG COMPOUND:C07759 ChEBI:3047 DrugBank:DB00562 Wikipedia:Benzthiazide NIST Chemistry WebBook:91-33-8 PubChem Compound:2343 |
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| subClassOf |