loading...| Preferred Name |
methoxsalen |
|
| Synonyms |
8-Methoxyfuranocoumarin Meloxine 8-methoxy-4',5':6,7-furocoumarin Xanthotoxin Ultra Mop 8-methoxy-2',3',6,7-furocoumarin Methoxsalen 8-MP 9-methoxy-7H-furo[3,2-g]chromen-7-one 6-hydroxy-7-methoxy-5-benzofuranacrylic acid delta-lactone 9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one 8-methoxy-[furano-3'.2':6.7-coumarin] METHOXSALEN 8-methoxypsoralen Uvadex Meladinine C12H8O4 O-methylxanthotoxol 8-MOP Oxsoralen 9-methoxy-2H-furo[3,2-g]chromen-2-one |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_18358 |
|
| AHFScode |
84:50.06 |
|
| altId |
CHEBI:27331 CHEBI:21960 CHEBI:12268 CHEBI:101063 CHEBI:27330 CHEBI:12715 CHEBI:10068 CHEBI:40342 |
|
| ATCCode |
D05AD02 D05BA02 |
|
| CASRN |
298-81-7 |
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| DBBrand |
meladinine meloxine uvadex deltasoralen oxsoralen ultramop |
|
| DBname |
methoxsalen |
|
| DBSynonym |
xanthotoxine zanthotoxin methoxalen xanthoxin xanthotoxin |
|
| Definition |
A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis. |
|
| has effect |
http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000303 http://purl.obolibrary.org/obo/OAE_0000557 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000660 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0000084 http://purl.obolibrary.org/obo/OAE_0001200 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0002206 |
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| has pharmacological target | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_47868 http://purl.obolibrary.org/obo/CHEBI_35610 |
|
| InChI |
InChI=1S/C12H8O4/c1-14-12-10-8(4-5-15-10)6-7-2-3-9(13)16-11(7)12/h2-6H,1H3 |
|
| InChIKey |
InChIKey=QXKHYNVANLEOEG-UHFFFAOYSA-N |
|
| inhibits |
http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_0294 |
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| is metabolised by | ||
| label |
methoxsalen |
|
| may interact with |
http://purl.obolibrary.org/obo/CHEBI_8107 http://purl.obolibrary.org/obo/CHEBI_4888 http://purl.obolibrary.org/obo/dinto_DB00532 http://purl.obolibrary.org/obo/CHEBI_63629 http://purl.obolibrary.org/obo/dinto_DB00382 |
|
| prefixIRI |
obo2:CHEBI_18358 |
|
| prefLabel |
methoxsalen |
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| related with | ||
| SMILES |
COc1c2occc2cc2ccc(=O)oc12 COC1=C2OC(=O)C=CC2=CC2=C1OC=C2 |
|
| Synonym |
8-Methoxyfuranocoumarin Meloxine 8-methoxy-4',5':6,7-furocoumarin Xanthotoxin Ultra Mop 8-methoxy-2',3',6,7-furocoumarin Methoxsalen 8-MP 9-methoxy-7H-furo[3,2-g]chromen-7-one 6-hydroxy-7-methoxy-5-benzofuranacrylic acid delta-lactone 9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one 8-methoxy-[furano-3'.2':6.7-coumarin] METHOXSALEN 8-methoxypsoralen Uvadex Meladinine C12H8O4 O-methylxanthotoxol 8-MOP Oxsoralen 9-methoxy-2H-furo[3,2-g]chromen-2-one |
|
| xref |
ChemSpider:3971 National Drug Code Directory:0187-0651-42 PharmGKB:PA450433 Drugs Product Database (DPD):698059 Beilstein:196453 KEGG COMPOUND:C01864 Wikipedia:Methoxsalen Patent:US2889337 RxList:http://www.rxlist.com/cgi/generic2/methox.htm PubChem Substance:46506275 PDBeChem:8MO Drugs.com:http://www.drugs.com/cdi/methoxsalen-hard-gelatin-capsules.html PubChem Compound:4114 NIST Chemistry WebBook:298-81-7 CASRN:298-81-7 DrugBank:DB00553 PDB:8MO ChEBI:18358 KEGG DRUG:D00139 Wikipedia:http://en.wikipedia.org/wiki/Methoxsalen |
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| subClassOf |