The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

methoxsalen

Synonyms

8-MOP

Oxsoralen

9-methoxy-2H-furo[3,2-g]chromen-2-one

8-methoxy-[furano-3'.2':6.7-coumarin]

8-methoxy-2',3',6,7-furocoumarin

6-hydroxy-7-methoxy-5-benzofuranacrylic acid delta-lactone

Uvadex

9-methoxy-7H-furo[3,2-g]chromen-7-one

C12H8O4

Xanthotoxin

O-methylxanthotoxol

8-methoxy-4',5':6,7-furocoumarin

9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one

8-Methoxyfuranocoumarin

METHOXSALEN

Ultra Mop

8-MP

Meladinine

Methoxsalen

8-methoxypsoralen

Meloxine

ID

http://purl.obolibrary.org/obo/CHEBI_18358

AHFScode

84:50.06

altId

CHEBI:101063

CHEBI:12268

CHEBI:40342

CHEBI:12715

CHEBI:21960

CHEBI:10068

CHEBI:27330

CHEBI:27331

ATCCode

D05BA02

D05AD02

CASRN

298-81-7

DBBrand

ultramop

oxsoralen

meloxine

meladinine

deltasoralen

uvadex

DBname

methoxsalen

DBSynonym

zanthotoxin

xanthotoxine

xanthoxin

methoxalen

xanthotoxin

Definition

A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.

has effect

http://purl.obolibrary.org/obo/OAE_0000390

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000557

http://purl.obolibrary.org/obo/OAE_0001200

http://purl.obolibrary.org/obo/OAE_0002206

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0000084

http://purl.obolibrary.org/obo/OAE_0000645

http://purl.obolibrary.org/obo/OAE_0000303

http://purl.obolibrary.org/obo/OAE_0000660

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0000551

has pharmacological target

http://purl.obolibrary.org/obo/dinto_2873

has role

http://purl.obolibrary.org/obo/CHEBI_35610

http://purl.obolibrary.org/obo/CHEBI_50177

http://purl.obolibrary.org/obo/CHEBI_50684

http://purl.obolibrary.org/obo/CHEBI_47868

InChI

InChI=1S/C12H8O4/c1-14-12-10-8(4-5-15-10)6-7-2-3-9(13)16-11(7)12/h2-6H,1H3

InChIKey

InChIKey=QXKHYNVANLEOEG-UHFFFAOYSA-N

inhibits

http://purl.obolibrary.org/obo/dinto_2496

http://purl.obolibrary.org/obo/dinto_0269

http://purl.obolibrary.org/obo/dinto_2651

http://purl.obolibrary.org/obo/dinto_0294

is metabolised by

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_2496

label

methoxsalen

may interact with

http://purl.obolibrary.org/obo/dinto_DB01320

http://purl.obolibrary.org/obo/dinto_DB00382

http://purl.obolibrary.org/obo/dinto_DB01623

http://purl.obolibrary.org/obo/dinto_DB00532

http://purl.obolibrary.org/obo/CHEBI_8107

http://purl.obolibrary.org/obo/CHEBI_4888

http://purl.obolibrary.org/obo/CHEBI_63629

prefixIRI

obo2:CHEBI_18358

prefLabel

methoxsalen

related with

http://purl.obolibrary.org/obo/dinto_2873

SMILES

COc1c2occc2cc2ccc(=O)oc12

COC1=C2OC(=O)C=CC2=CC2=C1OC=C2

Synonym

8-MOP

Oxsoralen

9-methoxy-2H-furo[3,2-g]chromen-2-one

8-methoxy-[furano-3'.2':6.7-coumarin]

8-methoxy-2',3',6,7-furocoumarin

6-hydroxy-7-methoxy-5-benzofuranacrylic acid delta-lactone

Uvadex

9-methoxy-7H-furo[3,2-g]chromen-7-one

C12H8O4

Xanthotoxin

O-methylxanthotoxol

8-methoxy-4',5':6,7-furocoumarin

9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one

8-Methoxyfuranocoumarin

METHOXSALEN

Ultra Mop

8-MP

Meladinine

Methoxsalen

8-methoxypsoralen

Meloxine

xref

ChEBI:18358

Patent:US2889337

PDB:8MO

PDBeChem:8MO

RxList:http://www.rxlist.com/cgi/generic2/methox.htm

ChemSpider:3971

Beilstein:196453

Drugs Product Database (DPD):698059

Drugs.com:http://www.drugs.com/cdi/methoxsalen-hard-gelatin-capsules.html

KEGG COMPOUND:C01864

KEGG DRUG:D00139

PharmGKB:PA450433

Wikipedia:http://en.wikipedia.org/wiki/Methoxsalen

Wikipedia:Methoxsalen

PubChem Substance:46506275

NIST Chemistry WebBook:298-81-7

DrugBank:DB00553

CASRN:298-81-7

National Drug Code Directory:0187-0651-42

PubChem Compound:4114

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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http://purl.bioontology.org/ontology/UATC/D05BA02 ATC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#8046 OCHV LOOM
http://purl.bioontology.org/ontology/MESH/D008730 MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/6854 RXNORM LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000039499 PDQ LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D008730 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.494.770.500 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.150.446.794.500 RH-MESH LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C643 NCIT LOOM
http://purl.obolibrary.org/obo/CHEBI_18358 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_18358 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_18358 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_18358 GO-PLUS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_18358 OCMR LOOM
http://purl.obolibrary.org/obo/CHEBI_18358 OCMR SAME_URI
http://purl.obolibrary.org/obo/CHEBI_18358 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_18358 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_18358 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_18358 NIFSTD SAME_URI
http://purl.bioontology.org/ontology/UATC/D05AD02 ATC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147183 NDFRT LOOM
http://purl.bioontology.org/ontology/LNC/LP18383-7 LOINC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU004185 LOINC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0025684 OCHV LOOM
http://purl.bioontology.org/ontology/NDDF/002018 NDDF LOOM
http://purl.obolibrary.org/obo/DRON_00014318 DRON LOOM
http://purl.bioontology.org/ontology/VANDF/4018889 VANDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.830.219.446.794.500 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNMI/C-92820 SNMI LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/41062004 SNOMEDCT LOOM