loading...| Preferred Name |
tafluprost |
|
| Synonyms |
propan-2-yl (5Z)-7-[(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-phenoxybut-1-en-1-yl]-3,5-dihydroxycyclopentyl]hept-5-enoate C25H34F2O5 |
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| ID |
http://purl.obolibrary.org/obo/dinto_DB08819 |
|
| activates | ||
| AHFScode |
52:40.28 |
|
| ATCCode |
S01EE05 |
|
| CASRN |
209860-87-7 |
|
| DBBrand |
zioptan saflutan taflotan |
|
| DBSynonym |
afp-168 |
|
| Definition |
A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Chemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost was approved for use in the U.S. on February 10, 2012. |
|
| has pharmacological target | ||
| InChI |
InChI=1S/C25H34F2O5/c1-18(2)32-24(30)13-9-4-3-8-12-20-21(23(29)16-22(20)28)14-15-25(26,27)17-31-19-10-6-5-7-11-19/h3,5-8,10-11,14-15,18,20-23,28-29H,4,9,12-13,16-17H2,1-2H3/b8-3-,15-14+/t20-,21-,22+,23-/m1/s1 |
|
| InChIKey |
InChIKey=WSNODXPBBALQOF-VEJSHDCNSA-N |
|
| induces | ||
| label |
tafluprost |
|
| prefixIRI |
obo2:dinto_DB08819 |
|
| prefLabel |
tafluprost |
|
| SMILES |
CC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\C(F)(F)COC1=CC=CC=C1 |
|
| Synonym |
propan-2-yl (5Z)-7-[(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-phenoxybut-1-en-1-yl]-3,5-dihydroxycyclopentyl]hept-5-enoate C25H34F2O5 |
|
| xref |
Wikipedia:http://en.wikipedia.org/wiki/Tafluprost PharmGKB:PA165958432 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/vir1605.shtml ChEBI:66899 RxList:http://www.rxlist.com/zioptan-drug.htm Drugs.com:http://www.drugs.com/zioptan.html BindingDB:50008984 PDB:TFO Drugs Product Database (DPD):2240434 National Drug Code Directory:0006-3931-30 |
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| subClassOf |