Preferred Name |
belatacept |
|
Synonyms |
|
|
ID |
http://purl.obolibrary.org/obo/dinto_DB06681 |
|
AHFScode |
92:44 |
|
ATCCode |
L04AA28 |
|
CASRN |
706808-37-9 |
|
DBBrand |
nulojix |
|
DBSynonym |
lea29y bms-224818 |
|
Definition |
Belatacept is a recombinant fusion protein composed of the Fc fragment of a human IgG1 immunoglobulin linked to the extracellular domain of CTLA-4, which is a molecule crucial for T-cell costimulation. Belatacept selectively blocks the process of T-cell activation. It was developed by Bristol-Myers-Squibb. It differs from abatacept (Orencia) by only 2 amino acids. FDA approved on June 15, 2011. |
|
label |
belatacept |
|
may interact with |
http://purl.obolibrary.org/obo/dinto_DB08879 http://purl.obolibrary.org/obo/CHEBI_8764 |
|
prefixIRI |
obo2:dinto_DB06681 |
|
prefLabel |
belatacept |
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related with | ||
xref |
National Drug Code Directory:0003-0371-13 Wikipedia:http://en.wikipedia.org/wiki/Belatacept RxList:http://www.rxlist.com/nulojix-drug.htm Drugs.com:http://www.drugs.com/cdi/belatacept.html |
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subClassOf |