The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

belatacept

Synonyms
ID

http://purl.obolibrary.org/obo/dinto_DB06681

AHFScode

92:44

ATCCode

L04AA28

CASRN

706808-37-9

DBBrand

nulojix

DBSynonym

lea29y

bms-224818

Definition

Belatacept is a recombinant fusion protein composed of the Fc fragment of a human IgG1 immunoglobulin linked to the extracellular domain of CTLA-4, which is a molecule crucial for T-cell costimulation. Belatacept selectively blocks the process of T-cell activation. It was developed by Bristol-Myers-Squibb. It differs from abatacept (Orencia) by only 2 amino acids. FDA approved on June 15, 2011.

label

belatacept

may interact with

http://purl.obolibrary.org/obo/dinto_DB08879

http://purl.obolibrary.org/obo/CHEBI_8764

http://purl.obolibrary.org/obo/dinto_DB06372

http://purl.obolibrary.org/obo/CHEBI_71223

prefixIRI

obo2:dinto_DB06681

prefLabel

belatacept

related with

http://purl.obolibrary.org/obo/dinto_2184

http://purl.obolibrary.org/obo/dinto_2187

xref

National Drug Code Directory:0003-0371-13

Wikipedia:http://en.wikipedia.org/wiki/Belatacept

RxList:http://www.rxlist.com/nulojix-drug.htm

Drugs.com:http://www.drugs.com/cdi/belatacept.html

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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