The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

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Preferred Name	tocilizumab
Synonyms
ID	http://purl.obolibrary.org/obo/dinto_DB06273
AHFScode	92:36
ATCCode	L04AC07
CASRN	375823-41-9
DBBrand	actemra
DBSynonym	atlizumab mra roactemra? r-1569
Definition	Tocilizumab is a recombinant, humanized, anti-human interleukin 6 (IL-6) receptor monoclonal antibody that achieves a significant therapeutic response rate. The light chain is made up of 214 amino acids. The heavy chain is made up of 448 amino acids. The four polypeptide chains are linked intra- and inter-molecularly by disulfide bonds. FDA approved on January 8, 2010.
has pharmacological target	http://purl.obolibrary.org/obo/dinto_1472
label	tocilizumab
may interact with	http://purl.obolibrary.org/obo/CHEBI_9150 http://purl.obolibrary.org/obo/dinto_DB06674 http://purl.obolibrary.org/obo/dinto_DB00514 http://purl.obolibrary.org/obo/dinto_DB06372 http://purl.obolibrary.org/obo/CHEBI_7772
prefixIRI	obo2:dinto_DB06273
prefLabel	tocilizumab
related with	http://purl.obolibrary.org/obo/dinto_1472
xref	National Drug Code Directory:50242-137-01 Drugs.com:http://www.drugs.com/international/tocilizumab.html RxList:http://www.rxlist.com/actemra-drug.htm PharmGKB:PA165292659 Wikipedia:http://en.wikipedia.org/wiki/Tocilizumab
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/DRON_00019607	PDRO	LOOM
http://purl.obolibrary.org/obo/DRON_00019607	INBANCIDO	LOOM
http://purl.obolibrary.org/obo/DRON_00019607	HOIP	LOOM
http://purl.obolibrary.org/obo/DRON_00019607	COVID-19	LOOM
http://purl.obolibrary.org/obo/DRON_00019607	DRON	LOOM
http://purl.obolibrary.org/obo/DRON_00019607	CIDO	LOOM
http://purl.obolibrary.org/obo/DRON_00019607	ODNAE	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000180629	NDFRT	LOOM
http://purl.bioontology.org/ontology/NDDF/013198	NDDF	LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000713832	PDQ	LOOM
https://github.com/sap218/ocimido/blob/master/ontology/ocimido.owl#OCIMIDO_00294	OCIMIDO	LOOM
http://purl.bioontology.org/ontology/RXNORM/612865	RXNORM	LOOM
http://purl.obolibrary.org/obo/CHEBI_64360	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_64360	BERO	LOOM
http://purl.bioontology.org/ontology/ATC/L04AC07	ATC	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00026122	PMAPP-PMO	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000180629	INBANCIDO	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000180629	ODAE	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000180629	CIDO	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84217	NCIT	LOOM
https://github.com/sap218/coid/blob/master/coid.owl#COID_00481	COID	LOOM
http://purl.bioontology.org/ontology/MESH/C502936	MESH	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/444648007	SNOMEDCT	LOOM
http://www.drugbank.ca/drugs/DB06273	FTC	LOOM
https://go.drugbank.com/drugs/DB06273	MDM	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU065080	LOINC	LOOM
http://purl.bioontology.org/ontology/VANDF/4029705	VANDF	LOOM
http://bmi.utah.edu/ontologies/peontology/C1609165	RAO	LOOM
http://purl.bioontology.org/ontology/LNC/LP420287-7	LOINC	LOOM
http://purl.jp/bio/4/id/200906055820639940	IOBC	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C502936	RH-MESH	LOOM
http://purl.obolibrary.org/obo/NCIT_C84217	BERO	LOOM