The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

phenindamine

Synonyms

2-methyl-9-phenyl-1H,2H,3H,4H,9H-indeno[2,1-c]pyridine

C19H19N

ID

http://purl.obolibrary.org/obo/dinto_DB01619

ATCCode

R06AX04

blocks

http://purl.obolibrary.org/obo/dinto_1071

CASRN

82-88-2

DBBrand

thephorin

DBSynonym

phenindiamine

fenindamina [inn-spanish]

phenindaminum [inn-latin]

Definition

Phenindamine is an antihistamine. Phenindamine blocks the effects of the naturally occurring chemical histamine in your body. Antihistamines such as phenindamine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release. It is used to treat sneezing, runny nose, itching, watery eyes, hives, rashes, itching, and other symptoms of allergies and the common cold. Symptoms of a phenindamine overdose include extreme sleepiness, confusion, weakness, ringing in the ears, blurred vision, large pupils, dry mouth, flushing, fever, shaking, insomnia, hallucinations, and possibly seizures.

has pharmacological target

http://purl.obolibrary.org/obo/dinto_1071

InChI

InChI=1S/C19H19N/c1-20-12-11-16-15-9-5-6-10-17(15)19(18(16)13-20)14-7-3-2-4-8-14/h2-10,19H,11-13H2,1H3

InChIKey

InChIKey=ISFHAYSTHMVOJR-UHFFFAOYSA-N

label

phenindamine

may interact with

http://purl.obolibrary.org/obo/CHEBI_42944

http://purl.obolibrary.org/obo/dinto_DB00209

http://purl.obolibrary.org/obo/CHEBI_53289

http://purl.obolibrary.org/obo/dinto_DB00427

http://purl.obolibrary.org/obo/CHEBI_27796

http://purl.obolibrary.org/obo/dinto_DB00382

prefixIRI

obo2:dinto_DB01619

prefLabel

phenindamine

SMILES

CN1CCC2=C(C1)C(C1=CC=CC=C21)C1=CC=CC=C1

Synonym

2-methyl-9-phenyl-1H,2H,3H,4H,9H-indeno[2,1-c]pyridine

C19H19N

xref

PubChem Compound:11291

ChemSpider:10817

BindingDB:50089147

Drugs.com:http://www.drugs.com/mtm/phenindamine.html

PubChem Substance:46508187

PharmGKB:PA164750491

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

Delete Subject Author Type Created
No notes to display