Preferred Name |
phenindamine |
|
Synonyms |
2-methyl-9-phenyl-1H,2H,3H,4H,9H-indeno[2,1-c]pyridine C19H19N |
|
ID |
http://purl.obolibrary.org/obo/dinto_DB01619 |
|
ATCCode |
R06AX04 |
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blocks | ||
CASRN |
82-88-2 |
|
DBBrand |
thephorin |
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DBSynonym |
phenindiamine fenindamina [inn-spanish] phenindaminum [inn-latin] |
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Definition |
Phenindamine is an antihistamine. Phenindamine blocks the effects of the naturally occurring chemical histamine in your body. Antihistamines such as phenindamine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release. It is used to treat sneezing, runny nose, itching, watery eyes, hives, rashes, itching, and other symptoms of allergies and the common cold. Symptoms of a phenindamine overdose include extreme sleepiness, confusion, weakness, ringing in the ears, blurred vision, large pupils, dry mouth, flushing, fever, shaking, insomnia, hallucinations, and possibly seizures. |
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has pharmacological target | ||
InChI |
InChI=1S/C19H19N/c1-20-12-11-16-15-9-5-6-10-17(15)19(18(16)13-20)14-7-3-2-4-8-14/h2-10,19H,11-13H2,1H3 |
|
InChIKey |
InChIKey=ISFHAYSTHMVOJR-UHFFFAOYSA-N |
|
label |
phenindamine |
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may interact with |
http://purl.obolibrary.org/obo/CHEBI_42944 http://purl.obolibrary.org/obo/dinto_DB00209 http://purl.obolibrary.org/obo/CHEBI_53289 http://purl.obolibrary.org/obo/dinto_DB00427 |
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prefixIRI |
obo2:dinto_DB01619 |
|
prefLabel |
phenindamine |
|
SMILES |
CN1CCC2=C(C1)C(C1=CC=CC=C21)C1=CC=CC=C1 |
|
Synonym |
2-methyl-9-phenyl-1H,2H,3H,4H,9H-indeno[2,1-c]pyridine C19H19N |
|
xref |
PubChem Compound:11291 ChemSpider:10817 BindingDB:50089147 Drugs.com:http://www.drugs.com/mtm/phenindamine.html PubChem Substance:46508187 PharmGKB:PA164750491 |
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subClassOf |