The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

insulin glulisine

Synonyms
ID

http://purl.obolibrary.org/obo/dinto_DB01309

activates

http://purl.obolibrary.org/obo/dinto_0892

AHFScode

68:20.08

ATCCode

A10AB06

CASRN

207748-29-6

DBBrand

apidra solostar

apidra

Definition

Insulin glulisine is a biosynthetic, rapid-acting human insulin analogue produced in a non-pathogenic laboratory strain of _Escherichia coli_ (K12). This recombinant hormone differs from native human insulin in that the amino acid arginine at position B3 is replaced by lysine and the lysine at position B29 is replaced by glutamic acid. These structural modifications decrease hexamer formation, stabilize insulin glulisine monomers and increase the rate of absorption and onset of action compared to human insulin.

has pharmacological target

http://purl.obolibrary.org/obo/dinto_0892

induces

http://purl.obolibrary.org/obo/dinto_2651

label

insulin glulisine

may interact with

http://purl.obolibrary.org/obo/CHEBI_5000

http://purl.obolibrary.org/obo/CHEBI_4856

http://purl.obolibrary.org/obo/CHEBI_3750

http://purl.obolibrary.org/obo/CHEBI_3127

http://purl.obolibrary.org/obo/CHEBI_3441

http://purl.obolibrary.org/obo/CHEBI_2904

http://purl.obolibrary.org/obo/dinto_DB00052

http://purl.obolibrary.org/obo/CHEBI_2379

http://purl.obolibrary.org/obo/CHEBI_439329

prefixIRI

obo2:dinto_DB01309

prefLabel

insulin glulisine

xref

PDRhealth:http://www.pdrhealth.com/drugs/rx/rx-mono.aspx?contentFileNam

Drugs.com:http://www.drugs.com/mtm/insulin-glulisine.html

Wikipedia:http://en.wikipedia.org/wiki/Insulin_glulisine

National Drug Code Directory:0088-2502-05

RxList:http://www.rxlist.com/apidra-drug.htm

PharmGKB:PA164760859

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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