loading...| Preferred Name |
nystatin |
|
| Synonyms |
(21E,23E,25E,27E,31E,33E)-20-{[(3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy}-4,6,8,11,12,16,18,36-octahydroxy-35,37,38-trimethyl-2,14-dioxo-1-oxacyclooctatriaconta-21,23,25,27,31,33-hexaene-17-carboxylic acid C47H75NO17 |
|
| ID |
http://purl.obolibrary.org/obo/dinto_DB00646 |
|
| AHFScode |
08:14.28 84:04.08.28 |
|
| ATCCode |
D01AA01 A07AA02 G01AA01 |
|
| binds | ||
| CASRN |
1400-61-9 |
|
| DBBrand |
pedi-dri nystatin dihydrate mykacet nystop nystatin-triamcinolone acetonide pms nystatin mycolog-ii nystex nyaderm mytrex f barstatin 100 mykinac nilstat mycostatin candex nadostine korostatin |
|
| Definition |
Nystatin is a polyene antifungal drug to which many molds and yeasts are sensitive, including Candida spp. Nystatin has some toxicity associated with it when given intravenously, but it is not absorbed across intact skin or mucous membranes. It is considered a relatively safe drug for treating oral or gastrointestinal fungal infections. |
|
| has effect |
http://purl.obolibrary.org/obo/OAE_0000875 http://purl.obolibrary.org/obo/OAE_0000905 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000770 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000375 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0000355 |
|
| has pharmacological target | ||
| InChI |
InChI=1S/C47H75NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-35(65-47-45(60)42(48)44(59)30(4)64-47)26-39(56)41(46(61)62)38(55)24-34(52)23-37(54)36(53)20-19-31(49)21-32(50)22-33(51)25-40(57)63-29(3)28(2)43(27)58/h5-6,8,10-18,27-33,35-39,41-45,47,49-51,53-56,58-60H,7,9,19-26,48H2,1-4H3,(H,61,62)/b6-5+,10-8+,13-11+,14-12+,17-15+,18-16+/t27?,28?,29?,30-,31?,32?,33?,35?,36?,37?,38?,39?,41?,42+,43?,44-,45+,47?/m1/s1 |
|
| InChIKey |
InChIKey=ZDFDJJJGIRGMBE-AFARJNEBSA-N |
|
| label |
nystatin |
|
| prefixIRI |
obo2:dinto_DB00646 |
|
| prefLabel |
nystatin |
|
| SMILES |
C[C@H]1OC(OC2CC(O)C(C(O)CC(=O)CC(O)C(O)CCC(O)CC(O)CC(O)CC(=O)OC(C)C(C)C(O)C(C)\C=C\C=C\CC\C=C\C=C\C=C\C=C\2)C(O)=O)[C@@H](O)[C@@H](N)[C@@H]1O |
|
| Synonym |
(21E,23E,25E,27E,31E,33E)-20-{[(3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy}-4,6,8,11,12,16,18,36-octahydroxy-35,37,38-trimethyl-2,14-dioxo-1-oxacyclooctatriaconta-21,23,25,27,31,33-hexaene-17-carboxylic acid C47H75NO17 |
|
| xref |
Drugs Product Database (DPD):792667 Drugs.com:http://www.drugs.com/cdi/nystatin.html National Drug Code Directory:0574-2008-15 PubChem Compound:11953884 Wikipedia:http://en.wikipedia.org/wiki/Nystatin ChemSpider:10128183 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/myc1279.shtml RxList:http://www.rxlist.com/cgi/generic2/nystat.htm PharmGKB:PA450666 PubChem Substance:46504780 |
|
| subClassOf |