loading...| Preferred Name |
fluorometholone |
|
| Synonyms |
C22H29FO4 (1R,2S,8S,10S,11S,14R,15S,17S)-14-acetyl-1-fluoro-14,17-dihydroxy-2,8,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one |
|
| ID |
http://purl.obolibrary.org/obo/dinto_DB00324 |
|
| activates | ||
| AHFScode |
52:08.08 |
|
| ATCCode |
C05AA06 D07XB04 S01BA07 S01CB05 D10AA01 D07AB06 |
|
| binds |
http://purl.obolibrary.org/obo/dinto_2146 |
|
| CASRN |
426-13-1 |
|
| DBBrand |
loticort efflumidex trilcin cortilet fml forte fluor-op ursnon fml liquifilm flumetholon delmeson oxylone flarex fluaton |
|
| DBSynonym |
fluormetholone fluoromethalone fml fluormetholon |
|
| Definition |
A glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p732) |
|
| has effect |
http://purl.obolibrary.org/obo/OAE_0000589 http://purl.obolibrary.org/obo/OAE_0000561 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0001481 http://purl.obolibrary.org/obo/OAE_0000308 http://purl.obolibrary.org/obo/OAE_0001073 http://purl.obolibrary.org/obo/OAE_0000312 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0000789 |
|
| has pharmacological target | ||
| InChI |
InChI=1S/C22H29FO4/c1-12-9-17-15-6-8-21(27,13(2)24)20(15,4)11-18(26)22(17,23)19(3)7-5-14(25)10-16(12)19/h5,7,10,12,15,17-18,26-27H,6,8-9,11H2,1-4H3/t12-,15-,17-,18-,19-,20-,21-,22-/m0/s1 |
|
| InChIKey |
InChIKey=FAOZLTXFLGPHNG-KNAQIMQKSA-N |
|
| induces | ||
| is metabolised by | ||
| is substrate of | ||
| label |
fluorometholone |
|
| modulates | ||
| prefixIRI |
obo2:dinto_DB00324 |
|
| prefLabel |
fluorometholone |
|
| related with | ||
| SMILES |
[H][C@@]12CC[C@](O)(C(C)=O)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](C)C2=CC(=O)C=C[C@]12C |
|
| Synonym |
C22H29FO4 (1R,2S,8S,10S,11S,14R,15S,17S)-14-acetyl-1-fluoro-14,17-dihydroxy-2,8,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one |
|
| xref |
Drugs Product Database (DPD):2238568 PubChem Substance:46505984 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/fml1183.shtml PubChem Compound:9878 Wikipedia:http://en.wikipedia.org/wiki/Fluorometholone National Drug Code Directory:11980-228-05 RxList:http://www.rxlist.com/cgi/generic/fluorometholone.htm Drugs.com:http://www.drugs.com/cdi/fluorometholone.html ChemSpider:9494 PharmGKB:PA164781355 |
|
| subClassOf |