The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

tenecteplase

Synonyms
ID

http://purl.obolibrary.org/obo/dinto_DB00031

AHFScode

20:12.20

ATCCode

B01AD11

CASRN

191588-94-0

DBBrand

tnkase (genentech inc)

DBSynonym

t-plasminogen activator

tissue-type plasminogen activator precursor

t- pa

tpa

Definition

Tissue plasminogen activator (tPA). Tenecteplase is a 527 amino acid glycoprotein developed by introducing the following modifications to the complementary DNA (cDNA) for natural human tPA: a substitution of threonine 103 with asparagine, and a substitution of asparagine 117 with glutamine, both within the kringle 1 domain, and a tetra-alanine substitution at amino acids 296-299 in the protease domain.

has pharmacological target

http://purl.obolibrary.org/obo/dinto_2148

http://purl.obolibrary.org/obo/dinto_0504

label

tenecteplase

may interact with

http://purl.obolibrary.org/obo/dinto_DB00055

http://purl.obolibrary.org/obo/dinto_DB01404

http://purl.obolibrary.org/obo/CHEBI_9588

http://purl.obolibrary.org/obo/dinto_DB01381

http://purl.obolibrary.org/obo/dinto_DB06692

prefixIRI

obo2:dinto_DB00031

prefLabel

tenecteplase

related with

http://purl.obolibrary.org/obo/dinto_3086

http://purl.obolibrary.org/obo/dinto_3087

http://purl.obolibrary.org/obo/dinto_3059

http://purl.obolibrary.org/obo/dinto_3057

http://purl.obolibrary.org/obo/dinto_2603

http://purl.obolibrary.org/obo/dinto_1845

http://purl.obolibrary.org/obo/dinto_2148

http://purl.obolibrary.org/obo/dinto_0172

http://purl.obolibrary.org/obo/dinto_0504

http://purl.obolibrary.org/obo/dinto_3457

http://purl.obolibrary.org/obo/dinto_2165

xref

Drugs.com:http://www.drugs.com/mtm/tenecteplase.html

PharmGKB:PA164776757

National Drug Code Directory:50242-038-61

GenBank:L00153

Wikipedia:http://en.wikipedia.org/wiki/Tenecteplase

RxList:http://www.rxlist.com/cgi/generic2/tenecteplase.htm

Drugs Product Database (DPD):2244826

UniProtKB:P00750

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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