serine/threonine-protein kinase 12

ec 2.7.11.1

http://purl.obolibrary.org/obo/dinto_2123

May be directly involved in regulating the cleavage of polar spindle microtubules and is a key regulator for the onset of cytokinesis during mitosis. Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Phosphorylates 'Ser-10' and 'Ser-28' of histone H3 during mitosis

DrugBank Database

aurkb

serine/threonine-protein kinase 12

human

obo2:dinto_2123

serine/threonine-protein kinase 12

http://purl.obolibrary.org/obo/dinto_DB04703

http://purl.obolibrary.org/obo/dinto_DB07340

ec 2.7.11.1

aurora- and ipl1-like midbody-associated protein 1

aurora-related kinase 2

aim-1

aurora/ipl1- related kinase 2

stk-1

aurora-b

UniProt ID:Q96GD4

DrugBank:5817

http://purl.obolibrary.org/obo/dinto_000128