loading...| Preferred Name |
penciclovir |
|
| Synonyms |
2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-1,9-dihydro-6H-purin-6-one penciclovir 9-[2-hydroxy-1-(hydroxymethyl)-ethoxymethyl]guanine C10H15N5O3 9-(4-hydroxy-3-(hydroxymethyl)butyl)guanine penciclovirum PCV 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-6,9-dihydro-3H-purin-6-one PE2 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine 9-(4-hydroxy-3-hydroxymethylbut-1-yl)-guanine |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_7956 |
|
| AHFScode |
84:04.06 |
|
| altId |
CHEBI:44870 |
|
| ATCCode |
D06BB06 J05AB13 |
|
| CASRN |
39809-25-1 |
|
| DBBrand |
denavir |
|
| DBname |
penciclovir |
|
| DBSynonym |
penciclovirum [inn-latin] pe2 |
|
| Definition |
Guanine in which the hydrogen at position 9 is substituted by a 4-hydroxy-3-(hydroxymethyl)but-1-yl group. An antiviral drug, it is administered topically for treatment of herpes labialis. A prodrug, famciclovir, is used for oral administration. |
|
| has effect |
http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000308 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000317 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001356 |
|
| has pharmacological target | ||
| has role | ||
| InChI |
InChI=1S/C10H15N5O3/c11-10-13-8-7(9(18)14-10)12-5-15(8)2-1-6(3-16)4-17/h5-6,16-17H,1-4H2,(H3,11,13,14,18) |
|
| InChIKey |
InChIKey=JNTOCHDNEULJHD-UHFFFAOYSA-N |
|
| induces | ||
| inhibits | ||
| label |
penciclovir |
|
| may interact with |
http://purl.obolibrary.org/obo/CHEBI_4551 http://purl.obolibrary.org/obo/dinto_DB01370 http://purl.obolibrary.org/obo/dinto_DB01574 |
|
| prefixIRI |
obo2:CHEBI_7956 |
|
| prefLabel |
penciclovir |
|
| SMILES |
Nc1nc2n(CCC(CO)CO)cnc2c(=O)[nH]1 NC1=NC(=O)C2=C(N1)N(CCC(CO)CO)C=N2 |
|
| Synonym |
2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-1,9-dihydro-6H-purin-6-one penciclovir 9-[2-hydroxy-1-(hydroxymethyl)-ethoxymethyl]guanine C10H15N5O3 9-(4-hydroxy-3-(hydroxymethyl)butyl)guanine penciclovirum PCV 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-6,9-dihydro-3H-purin-6-one PE2 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine 9-(4-hydroxy-3-hydroxymethylbut-1-yl)-guanine |
|
| xref |
PharmGKB:PA450839 CASRN:39809-25-1 PDB:PE2 Wikipedia:Penciclovir CiteXplore:3040998 DrugBank:DB00299 PubChem Substance:46506498 ChemSpider:4563 KEGG COMPOUND:C07417 Drugs.com:http://www.drugs.com/cdi/penciclovir.html Reaxys:4501039 HMDB:HMDB14444 ChEMBL:530597 Patent:US5075445 PubChem Compound:4725 KEGG DRUG:D05407 National Drug Code Directory:0067-6024-15 ChEBI:7956 PDBeChem:PE2 RxList:http://www.rxlist.com/cgi/generic3/penciclovir.htm Wikipedia:http://en.wikipedia.org/wiki/Penciclovir |
|
| subClassOf |