loading...| Preferred Name |
paromomycin sulfate |
|
| Synonyms |
aminosidine sulfate (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside sulfate aminosidin sulfate aminosidine sulphate C23H45N5O14.(H2O4S)n Humatin C23H45N5O14 (2R,3S,4R,5R,6S)-5-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}-3-hydroxycyclohexyl]oxy}-2-(hydroxymethyl)oxane-3,4-diol |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_7935 |
|
| AHFScode |
08:30.04 |
|
| ATCCode |
A07AA06 |
|
| CASRN |
1263-89-4 |
|
| DBBrand |
humatin |
|
| DBname |
paromomycin |
|
| DBSynonym |
aminosidin paramomycin sulfate aminosidine |
|
| Definition |
An aminoglycoside sulfate salt resulting from the treatment of paromomycin with sulfuric acid. A broad-spectrum antibiotic, it is used for the treatment of acute and chronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections. It is also used as a therapeutic against visceral leishmaniasis. |
|
| has effect | ||
| has pharmacological target | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_35820 http://purl.obolibrary.org/obo/CHEBI_36047 |
|
| InChI |
InChI=1S/C23H45N5O14/c24-2-7-13(32)15(34)10(27)21(37-7)41-19-9(4-30)39-23(17(19)36)42-20-12(31)5(25)1-6(26)18(20)40-22-11(28)16(35)14(33)8(3-29)38-22/h5-23,29-36H,1-4,24-28H2/t5-,6+,7+,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+/m1/s1 |
|
| InChIKey |
InChIKey=UOZODPSAJZTQNH-LSWIJEOBSA-N |
|
| inhibits | ||
| label |
paromomycin sulfate |
|
| prefixIRI |
obo2:CHEBI_7935 |
|
| prefLabel |
paromomycin sulfate |
|
| SMILES |
NC[C@@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@@H](O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O)[C@H](N)[C@@H](O)[C@@H]1O |
|
| Synonym |
aminosidine sulfate (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside sulfate aminosidin sulfate aminosidine sulphate C23H45N5O14.(H2O4S)n Humatin C23H45N5O14 (2R,3S,4R,5R,6S)-5-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}-3-hydroxycyclohexyl]oxy}-2-(hydroxymethyl)oxane-3,4-diol |
|
| xref |
CASRN:1263-89-4 National Drug Code Directory:61570-529-10 Drugs.com:http://www.drugs.com/cdi/paromomycin.html CiteXplore:17582067 Wikipedia:Paromomycin_sulfate Reaxys:21343285 RxList:http://www.rxlist.com/cgi/generic/humatin.htm PharmGKB:PA164784023 Drugs Product Database (DPD):2078759 ChemSpider:145115 CiteXplore:18447603 Wikipedia:http://en.wikipedia.org/wiki/Paromomycin_sulfate CiteXplore:8036682 KEGG DRUG:D00868 PubChem Substance:46505391 DrugBank:DB01421 PubChem Compound:165580 |
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| subClassOf |